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Allogeneic Mesenchymal Stem Cell Transplantation in Tibial Closed Diaphyseal Fractures

Tibial Fracture Clinical Trial

Official title:
Evaluation the Safety and Efficacy of Allogeneic Mesenchymal Stem Cell Transplantation in Tibial Closed Diaphyseal Fractures

Clinical Trial Summary

This study is a case-control prospective, clinal trial to assess the safety and efficacy of the allogeneic adipose derived mesenchymal stem cell transplantation on the healing of recent tibial fracture in 40 patients.

Clinical Trial Description

In this study all eligible patients divided in 2 group.20 patients received allogeneic adipose derived mesenchymal stem cell in the fractured site (case group) and other patients received the placebo in the fractured site (control group) .

To assess the outcomes, we will evaluate the patients at 2, 6 weeks and 3, 6 months after transplantation by: X-ray, BMD , VAS and biochemical analysis with laboratory tests. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02140528
Study type Interventional
Source Royan Institute
Contact
Status Completed
Phase Phase 2
Start date August 2013
Completion date April 2016
View Details
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