Thyroid Dysfunction Clinical Trial
Official title:
Thyroid Dysfunction in Patients With Nephrotic Syndrome
This study is to evaluate Thyroid Hormone profile in patients with Nephrotic syndrome to identify clinical predictor of Thyroid dysfunction in patients with Nephrotic syndrome
Status | Not yet recruiting |
Enrollment | 100 |
Est. completion date | October 1, 2022 |
Est. primary completion date | October 1, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 80 Years |
Eligibility |
Inclusion Criteria: - Nephrotic syndrome defined by the following: 1. Generalized edema 2. Urine protein excretion > 3,5 g/24 hours 3. Urine protein to creatinine ratio > 3,500mg/g 4. Serum albumin level less than 30 g/L Exclusion Criteria: - 1) Patients < 18 years old 2) Patients who have Thyroid diseases, current or past history of thyroid hormone or antithyroid drug intake. 3) Patients who have diabetes mellitus or autoimmune diseases as systemic lupus erythematosus and RA 4) Medications known to affect thyroid function. 5) Patients with liver cirrhosis and chronic liver disease as augmentin |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Merna Makram | Assiut University |
Bradley SE, Stéphan F, Coelho JB, Réville P. The thyroid and the kidney. Kidney Int. 1974 Nov;6(5):346-65. — View Citation
McCloskey O, Maxwell AP. Diagnosis and management of nephrotic syndrome. Practitioner. 2017 Feb;261(1801):11-5. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Hypothyroidism in patients with nephrotic syndrome | Decrease T3 and/or T4 and/or increase TSH in patients with proteinurea more than 3.5 mg | 1year |
Status | Clinical Trial | Phase | |
---|---|---|---|
Not yet recruiting |
NCT01682785 -
Incidence of Metabolic Syndrome and Thyroid Dysfunction in Patients With Major Depressive Disorder
|
N/A | |
Completed |
NCT04470440 -
Thyroid Dysfunction and Nivolumab Reponse in NSCLC
|
||
Not yet recruiting |
NCT04809454 -
Frequency of Florid Hyperthyroidism In Patients Taking Iodinated Salt
|
||
Recruiting |
NCT05980923 -
Thyroid Profiles in Patients With Acute Illness
|
||
Recruiting |
NCT03754621 -
Upper Limit for TSH of First and Second Trimester Pregnancy in Turkey
|
||
Completed |
NCT04013308 -
Iontophoresis With Potassium Iodide and Thyroid Function
|
N/A | |
Completed |
NCT05385029 -
Fetal and Neonatal Thyroid in Pregnancies With Severe Acute Respiratory Syndrome Coronavirus 2 ( SARS- COV2 ) COVID-19
|
||
Not yet recruiting |
NCT06293534 -
Thyroid Dysfunction in Patients With Major Psychiatric Disorders
|
||
Terminated |
NCT03787303 -
Study of Euthyroid Hypothyroxinemia in Metastatic Breast Carcinoma
|
Phase 2 | |
Completed |
NCT02832960 -
The TRUST Trial - CardioVascular Imaging ECHO
|
Phase 4 | |
Completed |
NCT02832934 -
The TRUST Study - CardioVascular Imaging IMT
|
Phase 4 | |
Completed |
NCT00592514 -
Thyroid Dysfunction in Head and Neck Surgery Patients
|
N/A | |
Terminated |
NCT00504218 -
Detection and Treatment of Endocrine Abnormalities in Childhood Cancer Survivors and Hematopoietic Stem Cell Transplant Recipients
|
||
Active, not recruiting |
NCT04658524 -
Evaluation of Thyroid Function in Patients With Chronic Kidney Disease
|
||
Completed |
NCT02500342 -
Effect of Thyroid Hormone Replacement on Fatigability in Untreated Older Adults With Subclinical Hypothyroidism
|
Phase 4 | |
Completed |
NCT02491008 -
Novel Biomarkers and Skeletal Outcomes Associated With Subclinical Thyroid Dysfunction
|
Phase 4 | |
Not yet recruiting |
NCT06185309 -
Evaluation of Different Psychiatric Symptoms in Patients With Thyroid Dysfunction
|
||
Not yet recruiting |
NCT04613323 -
Management of Thyroid Function in Hashimoto's Thyroiditis During Pregnancy
|
||
Recruiting |
NCT04019509 -
The Influence of Different Thyroid Autoantibodies on Thyroid Function and Pregnancy Outcome After Assisted Reproductive Technology
|
N/A | |
Active, not recruiting |
NCT04439747 -
Develop and Implement Methods for Diagnostic and Treatment of Hormonal Disorders in Patients With Chronic Kidney Disease
|