Clinical Trial Details
— Status: Recruiting
Administrative data
NCT number |
NCT04873882 |
Other study ID # |
21550 |
Secondary ID |
|
Status |
Recruiting |
Phase |
|
First received |
|
Last updated |
|
Start date |
December 16, 2019 |
Est. completion date |
August 27, 2021 |
Study information
Verified date |
April 2021 |
Source |
University of Virginia |
Contact |
Allison J Bechtel, MD |
Phone |
434.924.2283 |
Email |
as4sk[@]hscmail.mcc.virginia |
Is FDA regulated |
No |
Health authority |
|
Study type |
Observational
|
Clinical Trial Summary
With the aid of computerized sound analysis, digital acoustic monitoring could provide a more
sensitive, specific, and quantifiable indicator for perioperative respiratory abnormalities
including wheezing. It is probable that the digital stethoscope has utility in the detection,
monitoring, and resolution following treatment of acoustic changes characteristic of
turbulent respiratory gas flow due to wheezing and/or the incomplete resolution of
atelectasis following the re-initiation of ventilation in a collapsed lung.
Description:
Anesthesiologists still rely on use of a conventional stethoscope to detect abnormal breath
sounds during and after surgery - this process is labor intensive, intermittent, relies on
human experience and thus is highly subjective. In fact, even for the most basic assessments,
e.g. endobronchial intubation, human auscultation is unreliable.1 Digital stethoscopes are
able to both amplify and digitize airway sounds and also provide a mechanism to record and
analyze them for features undetectable by a human. Several small, pilot studies have shown
that acoustic waveforms from the lungs produce characteristic spectral patterns in specific
pulmonary pathophysiologic states. At this time, there are no studies that examine the
acoustic patterns specific to perioperative wheezing or lung re-expansion. With the aid of
computerized sound analysis, digital acoustic monitoring could provide a more sensitive,
specific, and quantifiable indicator for perioperative respiratory abnormalities including
wheezing. It is probable that the digital stethoscope has utility in the detection and
monitoring of acoustic changes characteristic of turbulent respiratory gas flow due to
wheezing and/or the incomplete resolution of atelectasis following the re-initiation of
ventilation in a collapsed lung. In addition, treatment of perioperative wheezing with an
inhaled bronchodilator may lead to resolution of wheezing and this response to treatment may
also be monitored using waveform and spectral characteristics of the acoustic patterns from
the digital stethoscope.