Thoracic Surgery Clinical Trial
Official title:
Reduction of Post-Operative Urinary Retention With Tamsulosin Versus Placebo (REPOURT- P) Trial
The purpose of this study are to determine the efficacy of tamsulosin compared to placebo in reducing post-operative urinary retention and improving other clinical outcomes in people undergoing thoracic surgery.
Post-operative urinary retention (POUR) is not an uncommon complication following thoracic surgery. It has been reported to occur in up to 12-67% of patients with the use of thoracic epidural analgesia1. Risk factors associated with urinary retention in thoracic patients include male, age over 40 years, type 2 diabetes, undergoing lung resection and the use of thoracic epidural analgesia2. Patients who experience urinary retention are treated with a straight catheter and may subsequently require the placement of an indwelling catheter. The use of these catheters is associated with numerous complications. The best studied complications are infectious and include catheter associated urinary tract infections (CAUTIs). However, many patients continue to experience symptoms well after their catheters have been removed. Tamsulosin is an alpha one adrenergic receptor blocked that is indicated for the treatment of lower urinary tract symptoms in the context of benign prostatic hyperplasia. However, it is often used in clinical practice to treat other pathologies such as acute urinary retention and nephrolithiasis. The objectives of this study are to determine the efficacy of tamsulosin compared to placebo in reducing post-operative urinary retention and catheter related complications in people undergoing thoracic surgery. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04865874 -
GDT-PPV Protocol in Thoracic Surgery
|
N/A | |
| Active, not recruiting |
NCT02715271 -
Study of TB Lesions Obtained in Therapeutical Surgery
|
||
| Completed |
NCT02964026 -
Study of Clinical Outcomes Associated With the Pulmonary Artery Catheter (PAC) in Cardiac Surgery Patients
|
N/A | |
| Completed |
NCT02919267 -
Physiology of Lung Collapse Under One-Lung Ventilation: Underlying Mechanisms
|
N/A | |
| Recruiting |
NCT03165539 -
Cerebral Oxygen Desaturation and Post-Operative Delirium in Thoracic Surgical Patients
|
||
| Terminated |
NCT01320475 -
Epidural Levobupivacaine-sufentanil Versus Epidural Levobupivacaine and Intravenous Ketamine
|
Phase 4 | |
| Recruiting |
NCT05045196 -
Health-promoting Family Conversations and Open Heart Surgery
|
N/A | |
| Completed |
NCT04507958 -
Electronic Stethoscope Use During Intubation in Full Personal Protective Equipment
|
||
| Recruiting |
NCT05060302 -
Prognosis of Right Ventricular Dysfunction Assessed by Speckle Tracking in Postoperative Thoracic Surgery
|
N/A | |
| Completed |
NCT05667467 -
The Effect of Care Bundle in Heart Surgery
|
N/A | |
| Not yet recruiting |
NCT03275428 -
THRIVE and Non-intubated Thoracic Surgery
|
N/A | |
| Not yet recruiting |
NCT05482230 -
Application of Tracheal Intubation in Lateral Position in Thoracic Surgery
|
N/A | |
| Enrolling by invitation |
NCT04429009 -
A Randomized Control Trial of ZEPHYRx Gamified Incentive Spirometry Compared to Traditional Spirometry
|
N/A | |
| Not yet recruiting |
NCT03628040 -
Erector Spinae Plane Block for Video-assisted Thoracoscopic Surgery
|
Phase 3 | |
| Recruiting |
NCT03300622 -
Assessment in Patients After Thoracic Surgery
|
N/A | |
| Completed |
NCT00981474 -
Cerebral Autoregulation Monitoring During Cardiac Surgery
|
N/A | |
| Completed |
NCT03309280 -
Influence of Different Parameters on Extubation Time After Cardiac Surgery.
|
||
| Recruiting |
NCT03820700 -
Using Hypnosis and Virtual Reality During Pre and Postoperative Cardiovascular Surgery.
|
N/A | |
| Completed |
NCT03768193 -
Deep Serratus Anterior Plane Block vs Surgically-placed Paravertebral Block for VATS Surgery
|
N/A | |
| Recruiting |
NCT04609228 -
Cardiac Surgery Outcomes in Blood-transfusion Acceptors and no Acceptors
|