Thoracic Surgery Clinical Trial
Official title:
The Effect of the Ultrasound-guided Serratus Anterior Plane Block in Combinaison With Thoracic Paravertebral cathéter Versus Thoracic Paravertebral Cather for Perioperative Analgesia in Thoracic Surgery
Verified date | July 2019 |
Source | Centre Hospitalier Universitaire Dijon |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Introduction
The paravertebral catheter has been shown to be effective in controlling postoperative pain,
but has never been associated with the deep dentate block in thoracic surgery. The objective
of this study was to compare the efficacy of single-dose deep dentate block-level
postoperative pain control in combination with a continuous perfusion paravertebral catheter
versus continuous perfusion paravertebral catheter alone in controlled thoracic surgery.
Materials and methods
We retrospectively included 159 ASA I-III major patients who underwent scheduled thoracic
surgery in the operating theater of Dijon University Hospital, between March and November
2018. All patients benefited from the same anesthetic protocol routinely used in controlled
thoracic surgery. They were included in two groups: deep serrate deep group (GS) with a deep
serrated deep serrate block immediately after orotracheal intubation with 0.2% Ropivacaine at
0.75 mg / kg and paravertebral catheter placed by the surgeon and put in charge at the fall
of the surgical drapes versus control group (GC) benefiting from a paravertebral catheter
alone. The primary endpoint was 24-hour morphine equivalent consumption. The criteria for
secondary judgments were intraoperative remifentanil consumption, VAS at 0h, 24h and 48h,
morphine consumption at 0h, 48h and the profile of the various complications. The morphine
equivalent was calculated according to an equivalence table with reference to Oxycodone per
os. Quantitative data are presented in median and standard deviation and were compared by
Student's t-test or Wilcoxon test.
Status | Completed |
Enrollment | 159 |
Est. completion date | June 1, 2019 |
Est. primary completion date | November 1, 2018 |
Accepts healthy volunteers | |
Gender | All |
Age group | 18 Years to 100 Years |
Eligibility |
Inclusion Criteria: - We included all patients over the age of 18 who met the classification criteria of the American Society of Anesthesiology (ASA) and had thoracic surgery in the operating theater of Dijon University Hospital Exclusion Criteria: - Exclusion criteria were ASA 4 or higher, pregnant or breastfeeding women, minor patients, patients not able to use morphine PCA, and patients with chronic algia. |
Country | Name | City | State |
---|---|---|---|
France | Chu Dijon Bourgogne | Dijon |
Lead Sponsor | Collaborator |
---|---|
Centre Hospitalier Universitaire Dijon |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | consumption of morphine equivalence | 24 hours | ||
Secondary | intraoperative remifentanil consumption, | 48 hours | ||
Secondary | visual analogue scale | 48 hours | ||
Secondary | morphine consumption | 48 hours | ||
Secondary | intraoperative complications | Day 5 |
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