Open Lung PEEP in Thoracic Surgery

Status Completed

Clinical Trial Summary

During thoracic surgical procedures, while ventilating with a protective tidal volume, an open lung approach consisting of a recruitment maneuver followed by an individualized positive end-expiratory pressure (PEEP) titrated to best respiratory system compliance (Open-lung PEEP, OL-PEEP) would decrease driving pressure. To test this hypothesis, we performed a multicenter observational study in 17 Spanish teaching hospitals of patients undergoing one lung ventilation (OLV). In addition, we analyzed the association between the driving pressure and the prevalence of postoperative pulmonary complications (PPCs), and finally the association between the individualized PEEP and relevant patient preoperative or intraoperative variables.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Thoracic Surgery
Ventilation Therapy; Complications

Clinical Trial Details

NCT number	NCT03184974
Study type	Observational [Patient Registry]
Source	Fundación para la Investigación del Hospital Clínico de Valencia
Contact
Status	Completed
Phase	N/A
Start date	October 1, 2015
Completion date	November 1, 2016

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04865874` - GDT-PPV Protocol in Thoracic Surgery	N/A
Active, not recruiting	`NCT02715271` - Study of TB Lesions Obtained in Therapeutical Surgery
Completed	`NCT02964026` - Study of Clinical Outcomes Associated With the Pulmonary Artery Catheter (PAC) in Cardiac Surgery Patients	N/A
Completed	`NCT02919267` - Physiology of Lung Collapse Under One-Lung Ventilation: Underlying Mechanisms	N/A
Recruiting	`NCT03165539` - Cerebral Oxygen Desaturation and Post-Operative Delirium in Thoracic Surgical Patients
Terminated	`NCT01320475` - Epidural Levobupivacaine-sufentanil Versus Epidural Levobupivacaine and Intravenous Ketamine	Phase 4
Recruiting	`NCT05045196` - Health-promoting Family Conversations and Open Heart Surgery	N/A
Completed	`NCT04507958` - Electronic Stethoscope Use During Intubation in Full Personal Protective Equipment
Recruiting	`NCT05060302` - Prognosis of Right Ventricular Dysfunction Assessed by Speckle Tracking in Postoperative Thoracic Surgery	N/A
Completed	`NCT05667467` - The Effect of Care Bundle in Heart Surgery	N/A
Not yet recruiting	`NCT03275428` - THRIVE and Non-intubated Thoracic Surgery	N/A
Not yet recruiting	`NCT05482230` - Application of Tracheal Intubation in Lateral Position in Thoracic Surgery	N/A
Enrolling by invitation	`NCT04429009` - A Randomized Control Trial of ZEPHYRx Gamified Incentive Spirometry Compared to Traditional Spirometry	N/A
Not yet recruiting	`NCT03628040` - Erector Spinae Plane Block for Video-assisted Thoracoscopic Surgery	Phase 3
Recruiting	`NCT03300622` - Assessment in Patients After Thoracic Surgery	N/A
Completed	`NCT00981474` - Cerebral Autoregulation Monitoring During Cardiac Surgery	N/A
Completed	`NCT03309280` - Influence of Different Parameters on Extubation Time After Cardiac Surgery.
Recruiting	`NCT03820700` - Using Hypnosis and Virtual Reality During Pre and Postoperative Cardiovascular Surgery.	N/A
Completed	`NCT03768193` - Deep Serratus Anterior Plane Block vs Surgically-placed Paravertebral Block for VATS Surgery	N/A
Recruiting	`NCT04609228` - Cardiac Surgery Outcomes in Blood-transfusion Acceptors and no Acceptors