Thoracic Surgery Clinical Trial
Official title:
Desflurane and Its Effect on Postoperative Morbidity and Mortality in Patients Undergoing Thoracic Surgery
Desflurane and its effect on postoperative morbidity and mortality in patients undergoing
thoracic surgery.
Halothane, enflurane, isoflurane, sevoflurane, and desflurane are volatile anesthetics, a
group of general anesthetics. Because of the hypnotic effects of these agents, attention has
mainly focused on the central nervous system. In the last 10 years, however, numerous
studies have reported that volatile anesthetic agents interact with membrane structures of
the myocardium and thereby attenuate cardiac mechanical dysfunction and limit
ultrastructural abnormality on reperfusion after prolonged ischemia in the myocyte.
Anesthetic-induced preconditioning has become a main topic in cardiac research worldwide
- Trial with medicinal product
n/a
Allocation: Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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