Mobilization With Movement on Pain, Function, and Quality of Life in Patients With Thoracic Outlet Syndrome

Thoracic Outlet Syndrome Clinical Trial

Official title:

The Impact of Mobilization With Movement on Pain, Function, and Quality of Life in Patients With Thoracic Outlet Syndrome: A Randomized Controlled Trial

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05917756
• Other study ID #: 012/0333666
• Status: Recruiting
• Phase: N/A
• Start date: July 1, 2023
• Est. completion date: July 1, 2024

Study information

• Verified date: June 2023
• Source: Ahram Canadian University
• Contact: Mohamed M ElMeligie, Ph.d
• Phone: +201064442032
• Email: mohamed.elmeligie[@]acu.edu.eg
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This randomized controlled trial aims to evaluate the effects of Mobilization with Movement (MWM) on pain, function, and quality of life in patients with Thoracic Outlet Syndrome (TOS) compared to conventional physiotherapy.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 120
• Est. completion date: July 1, 2024
• Est. primary completion date: July 1, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Adults aged 18-65 years, diagnosed with TOS by a specialist, and experiencing symptoms for at least 3 months

Exclusion Criteria:

• Previous surgery for TOS

• contraindications to manual therapy

• other comorbidities significantly affecting upper limb function

Related Conditions & MeSH terms

• Syndrome
• Thoracic Outlet Syndrome

Intervention

Other:
• Mobilization with Movement (MWM) and Tailored Therapeutic Exercise Program
The intervention consists of MWM techniques targeting the cervical and thoracic spine, and the first rib, applied by a certified physiotherapist for 8 weeks, 2 sessions per week, each session lasting 45 minutes. The intervention also includes a tailored therapeutic exercise program for the patients, comprising postural correction, stretching, and strengthening exercises. This intervention will be compared to conventional physiotherapy in the control group.
• Conventional Physiotherapy
Conventional physiotherapy, including manual therapy (soft tissue mobilization, joint mobilization, and nerve gliding techniques) for 8 weeks, 2 sessions per week, each session lasting 45 minutes, combined with a tailored therapeutic exercise program (including postural correction, stretching, and strengthening exercises).

Locations

Country	Name	City	State
Egypt	Outpatient clinic of faculty of physical therapy, Ahram Canadian University	Al ?ayy Ath Thamin	Giza

Sponsors (1)

Lead Sponsor	Collaborator
Ahram Canadian University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Changes in Pain Intensity	Pain intensity will be assessed using the Numeric Pain Rating Scale (NPRS).	Changes in Pain intensity at Baseline, 4 weeks, 8 weeks, and 12 weeks (follow-up)
Secondary	Changes in Functional Status	Functional status will be evaluated using the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire.	Changes in Functional Status Baseline, 4 weeks, 8 weeks, and 12 weeks (follow-up)
Secondary	Changes in Cervical Range of Motion	Cervical range of motion will be assessed using a goniometer.	Baseline, 4 weeks, 8 weeks, and 12 weeks (follow-up)
Secondary	Changes in Quality of Life	Quality of life will be assessed using the Short Form-36 (SF-36) questionnaire	Changes in quality of life at Baseline, 4 weeks, 8 weeks, and 12 weeks (follow-up)aseline, 4 weeks, 8 weeks, and 12 weeks (follow-up)