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Clinical Trial Summary

Thoracic insufficiency syndrome (TIS) is a complex condition that involves chest wall deformities that can affect normal breathing and lung growth. In most cases, children with TIS are also born with spine disorders such as scoliosis. The inability of the thorax to support normal respiration or lung growth can cause respiratory distress and even mortality. Investigators aim to validate MRI imaging sequences to use as an assessment tool for pulmonary function.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04977830
Study type Interventional
Source Children's Hospital of Philadelphia
Contact Hamidou Keita
Phone 267-426-5433
Email keitah@chop.edu
Status Recruiting
Phase N/A
Start date December 2024
Completion date August 30, 2025

See also
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Completed NCT01716936 - A Retrospective Review of Early Onset Spinal Deformity Patients Treated With the Ellipse MAGEC System N/A
Withdrawn NCT00585234 - Tools for the Objective Clinical Assessment of Pediatric Spinal Deformity