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Third Molar clinical trials

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NCT ID: NCT05860686 Not yet recruiting - Third Molar Clinical Trials

Does Post-operative Rinsing With a Monoject Syringe Result in as Much Post-operative Pain After Surgical Removal of Lower Impact Third Molars as no Post-operative Rinsing: a Randomized Controlled Equivalence Trial

RITOR
Start date: June 1, 2023
Phase: N/A
Study type: Interventional

Many authors have advocated different methods of treating alveolar osteitis. Despite many years of research, however, little progress has been made and so a study with large enough sample and standard outcome measures is warranted. Goal of this study is assess the effect of postoperative use of a monoject syringe on postoperative complaints after surgical removal of a lower third molar.

NCT ID: NCT05744882 Completed - Clinical trials for Impacted Third Molar Tooth

The Need Of Root Canal Treatment After Coronectomy In Mandibular Third Molars

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The study included 24 patients with written and verbal consent Results with close proximity to IAN diagnosed based on radiographs and evaluation on the criteria of Howe, and Poyton were selected and divided into two groups by lottery method into coronectomy and coronectomy with root canal treatment following coronectomy groups. Patients were re-evaluated on three weeks for complications and three months follow-ups for radiographic evaluations of root-fragment migration

NCT ID: NCT05044481 Completed - Clinical trials for Health-related Quality of Life

"Impact of the Third Molars in Oral Health-related Quality of Life"

Start date: February 5, 2019
Phase:
Study type: Observational

The aim of this study is to evaluate the impact of the third molars in oral health-related quality of life, before and after surgical removal using a validated and frequently used in international investigations instrument (OHIP-14).

NCT ID: NCT04641533 Completed - Periodontal Pocket Clinical Trials

Effect of Dental Pulp Stem Cells and L-PRF After Impacted Third Molar Extraction

Start date: January 20, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the clinical and radiographic effectiveness of Leukocyte-Platelet Rich Fibrin (L-PRF) and L-PRF combined with dental pulp stem cell (DPSC) application to the extraction socket of mandibular third molars.

NCT ID: NCT04143373 Completed - Surgical Blood Loss Clinical Trials

Effect of Warm Saline Irrigation on Bleeding in Mandibular Third Molar Surgery

Start date: October 1, 2017
Phase: N/A
Study type: Interventional

The objective of this research is to compare the effect of irrigation during impacted mandibular third molar surgery, with normal saline of 25 ± 2 ° C and 37 ± 1 ° C for control and experimental sides, respectively.

NCT ID: NCT03501225 Completed - Clinical Trial Clinical Trials

Effects of Ozonated Water on Pain, Swelling, Trismus and Quality of Life in Third Molar Surgery

Start date: November 8, 2017
Phase: N/A
Study type: Interventional

The aim of this study was to evaluate the effect of ozonated water on pain, edema and trismus after third molar removal. Patients were submitted to extraction of lower third molar under irrigation with ozonated water or doubly distilled water. Data were collected at baseline, 24 hours, 48 hours, 72 hours and 7 days after intervention.

NCT ID: NCT03398382 Active, not recruiting - Postoperative Pain Clinical Trials

Effect of Oral Magnesium on Anesthesia and Postoperative Analgesia After Surgical Removal of the Lower Third Molars.

Start date: April 15, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

The operation of the lower third molars is one of the most common oral surgery procedures in the world. The surgery is mostly done in local anesthesia which makes the surgery as pleasant as possible for the patient. In addition to anesthesia control, it is also extremely important to insure postoperative pain control since that is the nuisance that patients are most likely to complain about after oral surgery. It has been noticed that magnesium added to local anesthetics can improve and prolong its effect, but also reduce postoperative pain and accelerate recovery. It can also be used as an auxiliary to control pain and inflammation, which is why we will use it in this study, because we have not been able to find magnesium data in the literature for the removal of the lower third molars. Studies that have already been conducted with oral magnesium are for the purpose of preventing asthma, migraine, for reducing mood swings in PMS, reducing pain after endotracheal intubation, and many others. Removal by using operative procedure is the only way to remove lower third molars. The main objective of the study is to demonstrate the influence of the orally received magnesium citrate (before and after surgical removal of the lower third molar) on the quality and duration of the anesthetic block and also its effect on postoperative pain control. Other specific objectives are to investigate the effect of pre/postoperatively received magnesium on: 1. swelling stage after surgery. 2. time occurrence and duration of anesthesia. 3. trismus stage after the operative procedure. 4. the total amount of analgetics taken after surgery Benefits for the respondents will be in the assumption that the anesthetic block of the mandibular nerve will last longer with better quality, thus making the surgical procedure more pleasant and that the overall postoperative pain will be lessened and recovery faster in the magnesium citrate group. We also assume that in the magnesium citrate group trismus will be less pronounced and that swelling in postoperative days will be smaller.

NCT ID: NCT03130933 Completed - Clinical trials for Postoperative Complications

Complications After Lower Third Molar Surgery

Start date: April 2010
Phase: Phase 1/Phase 2
Study type: Interventional

Objectives: The objective of the study was to evaluate the effectiveness of a prophylactic single preoperative dose of amoxicillin in decreasing complications after lower third molar surgery. Materials and methods: The sample consisted of 400 patients randomly divided in two groups consisting of 200 patients per each group. The patients underwent third molar surgery at the Department of Oral Surgery, Clinical Hospital Dubrava, Croatia, in the period between April 2010. and November 2016. Unlike the patients from the second group, the first group of patients had never been diagnosed inflammation prior the surgical procedure. The main tested groups were further divided in two subgroups (control and tested): the tested subgroup (100 patients) received a prophylactic single dose of 2 g amoxicillin an hour prior the procedure, while the second control subgroup (100 patients) received a placebo. Complications, including swelling, alveolar osteitis (AO), infection at the surgical site (SSI), limited mouth opening, pain, bleeding, and increased body temperature, were evaluated postoperatively. Evaluation was done on the first postoperative day and 7 days after surgery.

NCT ID: NCT02696369 Completed - Third Molar Clinical Trials

Trial to Evaluate the Efficacy on Local Anesthesia and Safety of 2% Lidocaine HCl With Different Epinephrine Concentration in Patients Undergoing Surgical Extraction of Impacted Lower Third Molars

Start date: December 2014
Phase: Phase 4
Study type: Interventional

This study is Phase 4 trial which evaluates the safety and efficacy of 2% Lidocaine HCl with different epinephrine concentration in patients undergoing surgical extraction of impacted lower third molars