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NCT ID: NCT05591807 Completed - Tinnitus Clinical Trials

Investigation to the Mechanism of the Neuroplastic Modulation in Central Auditory Tract

Start date: July 2, 2019
Phase:
Study type: Observational

Tinnitus is the awareness of sound or noise in the absence of acoustic stimulation. No definite therapeutic strategy of tinnitus has been developed yet. The current theory of tinnitus is the plasticity theory of neurophysiology model. Although acupuncture has its role in tinnitus treatment, its actual role still remains to be elucidated. Acupuncture has been proposed to induce the development of neuroplasticity. The aim of this project is to undergo a comprehensive investigation to the central auditory effect and the therapeutic effects of acupuncture in tinnitus. According the results of the preliminary studies, the objective auditory measurement and subjective tinnitus perception will be analyzed in tinnitus patients before and after acupuncture.

NCT ID: NCT05279157 Completed - Keratoconus Clinical Trials

Autologous Adipose-Derived Adult Stem Cell Implantation for Corneal Diseases (ADASCs-CT-CD)

ADASCs-CT-CD
Start date: April 19, 2022
Phase: Phase 2
Study type: Interventional

Cellular therapy of the corneal stroma with implantation of mesenchymal stem cells derived from autologous adipose tissue with or without a carrier (scaffold) composed by decellularized human donor corneal stroma is used in patients with corneal diseases such as corneal dystrophies, and keratoconus. For this purpose, the study planned to assess the enhancement of visual acuity, pachymetric, and aberrometric parameters with implantation of autologous mesenchymal adipose tissue-derived adult stem cells (ADASCs) alone, 120 µm thickness of decellularized or recellularized laminas with ADASCs. Three groups will be included in the study: (1) Implantation of a single dose of ADASCs alone without scaffold. (2) Implantation of decellularized human corneal lamina without ADASCs. (3) Implantation of the recellularized human corneal lamina with ADASCs.

NCT ID: NCT05261503 Completed - Preterm Clinical Trials

Investigation of the Effectiveness of Environmental Enrichment-Based Intervention in Preterm Infants

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effectiveness the HEP (Homeostasis-Enrichment-Plasticity) approach, which based upon the principles of enriched environment (EE) and ecological theories of development on preterm infants with developmental delay risk. Thirty-two preterm infants aged 4-10 months will be randomly divided into 2 groups as the HEP intervention group and the Traditional Physical Therapy (TPT) group. EE-based intervention will be applied to the HEP intervention group, and traditional physiotherapy will be applied to the TPT group for 12 weeks (24 sessions). The demographic information of the participants will be recorded. The motor and sensory functions of the infants will be evaluated with, the Peabody Developmental Motor Scales (PDMS-2) and the Test of Sensory Functions in Infants™ (TSFI™), respectively. Additionally, the anxiety status of the parents will be evaluated with the Beck Anxiety Inventory (BAI). All evaluations will be done twice, at the end and at the beginning of 12 weeks.

NCT ID: NCT05190900 Completed - Rehabilitation Clinical Trials

Changes in Stabilometry After Neural Mobilisation in Foot

Start date: August 29, 2022
Phase: N/A
Study type: Interventional

Investigation will consist of measuring before and after applying nerve mobilization exercise. Measurements will be made on the same day without the need to go at another time. In this study, participants will be asked to stand on a pressure platform several times in a relaxed manner and with eyes open and closed before and after a neuromeningeal mobilization technique indicated for the treatment of pain in your feet. Measurements or tests to be carried out are totally innocuous and do not carry any risk to your health and integrity. Participants will have to remain barefoot for a maximum of 30 seconds, a total of 8 times on a pressure platform

NCT ID: NCT05190224 Completed - Rehabilitation Clinical Trials

Changes in Plantar Preassures and Ankle Range of Motion After the Technique of Neuromeningeal Mobilization

Start date: January 27, 2022
Phase: N/A
Study type: Interventional

Neuromeningeal mobilization or neurodynamics is a movement-based technique whose purpose is to restore peri- and intraneural homeostasis (1). It is based on principle that nerves have to lengthen and shorten to maintain normal muscle tension and range of motion (1) This technique has been shown to be effective in recovering tissue mobility (2), reducing pain in low back pain (3) and neck pain (1) and pain intensity in the elderly, and increasing joint range of motion and muscle flexibility (4 ) Regarding balance, sciatic nerve sliding has been shown to immediately improve balance to one leg ( dinamic balance) after application in a comparative study before and after (4,5) No study has been realised in for the Posterior Tibial, Deep Peroneal, Medial Dorsocutaneous and Lateral Nerves, and no study has verificated standing balance and range of motion in ankle joint

NCT ID: NCT05104957 Completed - Low Back Pain Clinical Trials

Evaluation of the Kinesiology Taping Effectiveness in the Treatment of Lumbar Spine Pain

Start date: November 15, 2021
Phase: N/A
Study type: Interventional

Lumbar spine pain syndromes are one of the most common pain conditions in our society. The purpose of kinesiotaping is to normalize muscle function, improve blood and lymph flow, reduce pain, improve proprioception, promote tissue healing and restore normal tissue function. Today, this method is used in many fields of medicine. Its primary purpose is to support the musculoskeletal system by using various types of applications. There is a lack of publications in the global literature on the effect of kinesiotaping of the external oblique muscles on lumbar spine pain. The main objective of this study is to evaluate the effectiveness of kinesiology taping in the treatment of lumbar spine pain in individuals under 30 years of age.

NCT ID: NCT04926311 Completed - Therapy Clinical Trials

Efficiency of Speech and Language Intervention on Achievement of Children With Developmental Language Disorder

DYSPHADEV
Start date: June 8, 2021
Phase:
Study type: Observational

Children with Developmental Language Disorder (DLD) have many linguistic difficulties in syntax, lexicon, morphology and phonology. Frequently, they also present co-occurrent (or comorbidities) impairments which further impaired school learning. Thus, they have poor academic outcomes and many of these children have been maintained at least one time in a classroom, sometime more. The purpose of this project is to determine which modalities of speech and language therapy are the more efficient on academic outcomes of children with DLD. The main modalities that will be studied are the duration of speech and language intervention, the age at which begins the intervention and the intensity (number of intervention sessions per week).

NCT ID: NCT04691310 Completed - Clinical trials for Head and Neck Cancer

The Efficacy of Kinesio Taping on Lymphedema Following Head and Neck Cancer Therapy

Start date: December 31, 2020
Phase: N/A
Study type: Interventional

Purpose off the study is investigating to efficacy of kinesio taping on neck lymphedema after the head and neck cancer therapy.

NCT ID: NCT04369079 Completed - Therapy Clinical Trials

Myofascial Versus Conventional Physiotherapy

MYONAMASTE
Start date: January 1, 2013
Phase: N/A
Study type: Interventional

A total of 61 patients who underwent total mastectomy for breast cancer with axillar lymph dissection and adjuvant radiotherapy were enrolled in this trial. The patients were randomized by toss of a coin to the treatment (n=30) or control (n=26) groups; of these, 48 met all study protocol requirements, including the final assessment. Inclusion criteria were: presence of functional difficulties in the shoulder area and/or upper torso on the surgical side, and 2) eligibility for physiotherapy (determined by the treating physician). Patients with recurrent disease and/or inflammatory or acute ailments were excluded. All patients gave their informed consent to participate in the study. The treatment group received myofascial treatment while patients in the control group received conventional therapy consisting of exercise and massage.

NCT ID: NCT03712748 Completed - Anorexia Nervosa Clinical Trials

Online Imaginal Exposure

Online IE
Start date: October 17, 2016
Phase: N/A
Study type: Interventional

This study evaluates if imaginal exposure therapy can decrease symptoms of eating disorders and anxiety, and test an online format of IE to maximize its ability to reach as many individuals with eating disorders as possible. All participants will complete four imaginal exposure sessions and will complete questionnaires prior to receiving this treatment, as well as complete follow up questionnaires at 1-month, 6-month, and 12-month.