Testicular Germ Cell Tumor Clinical Trial
Official title:
Sentinel Lymph Node Procedure in Testicular Germ Cell Tumour
Assessment of accuracy of sentinel node biopsy, defined as the false negative rate.
Current practice in patients with Clinical Stage I (CS I) testicular germ cell tumour is
active surveillance after orchiectomy, with relapses occurring in 15-20% of patients. The
majority of relapses occur in the lymph nodes as lymphogenic spread is the dominant route of
dissemination. A sentinel node procedure, in which the sentinel lymph node is resected and
pathologically examined, could be more reliable to identify patients who are likely to
relapse.
Early identification of patients with micro-metastases in the sentinel node makes it possible
to treat these patients at the earliest possible moment. Absence of metastases could lead in
the future to a less intensive follow up protocol than the present one.
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