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Clinical Trial Summary

Assessment of accuracy of sentinel node biopsy, defined as the false negative rate.


Clinical Trial Description

Current practice in patients with Clinical Stage I (CS I) testicular germ cell tumour is active surveillance after orchiectomy, with relapses occurring in 15-20% of patients. The majority of relapses occur in the lymph nodes as lymphogenic spread is the dominant route of dissemination. A sentinel node procedure, in which the sentinel lymph node is resected and pathologically examined, could be more reliable to identify patients who are likely to relapse.

Early identification of patients with micro-metastases in the sentinel node makes it possible to treat these patients at the earliest possible moment. Absence of metastases could lead in the future to a less intensive follow up protocol than the present one. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03448822
Study type Observational
Source The Netherlands Cancer Institute
Contact Joost Blok, MD
Phone 0031 20 5129111
Email j.blok@nki.nl
Status Not yet recruiting
Phase
Start date September 1, 2018
Completion date April 1, 2026

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