Test Meal Clinical Trial
Official title:
Fructose Extra-splanchnic Metabolism and Its Effects on Systemic Flux of Substrates (FruPP)
In parallel to the dramatic rise in metabolic diseases and diabetes observed over the past
fifty years, the generalization of added sugar in processed food led to a marked increase in
fructose consumption in almost all countries, and epidemiological studies demonstrated that
the consumption of sugar-sweetened beverage (containing at least 50% of fructose) is
associated with the development of diabetes, hepatic steatosis, dyslipidemia and obesity.
The objective of the study is to measure the amount of fructose that escape first-pass
hepatic extraction after oral ingestion (fructose+glucose), and gain insights into its
metabolic fates with the use of tracers.
n/a