The Platelet-Rich Plasma in the Therapy of Temporomandibular Disorders — PRP/TMD  

Temporomandibular Disorder Clinical Trial

Official title: The Platelet -Rich Plasma in the Therapy of Temporomandibular Disorders

Status Completed

Clinical Trial Summary

The Platelet-Rich Plasma intramuscular injections into the masseter and temporalis muscle were performed to reduce painful temporomandibular disorder symptoms,such as myalgia, myofascial pain and myofascial pain with referrals. Patients(n=120) were randomly divided into two groups: experimental(n=60) and control group(n=60). In controls injections with 0,9% NaCl were performed. Pain intensity was measured with NPRS (numeriic pain rating scale, 0= no pain, 11= the worst pain that one can imagine) before(0 day), during(10 day) and after(20 day) the therapy with PRP injections.

Clinical Trial Description

Patients(n=120) attending The Department of Temporomandibular Disorders and Orthodontics at the Silesian Medical University Poland, Zabrze were enrolled to the study and randomly divided into one of two groups: experimental and control group. Platelet-Rich Plasma(PRP) was prepared for each patient and an intramuscular injections of 0,5 ml PRP into 6 points at each side were performed in experimental group. A follow-up appointment was made after 10 and 20 days and in each visit an injection of PRP or 0,9% NaCl was performed. Pain intensity was measured in NPRS(numeric pain rating scale) and collected data data were analyzed. ;

Related Conditions & MeSH terms

• Bruxism
• Disease
• Myalgia
• PRP
• Temporomandibular Disorder
• Temporomandibular Joint Disorders
• Temporomandibular Joint Dysfunction Syndrome

• NCT number: NCT03371888
• Study type: Interventional
• Source: Medical University of Silesia
• Status: Completed
• Phase: Phase 2/Phase 3
• Start date: December 7, 2017
• Completion date: January 1, 2019