Clinical Trials Logo

Clinical Trial Summary

Purpose of the study is to compare clinically, radiographically and biochemically the effect of intra- articular injection of hypertonic dextrose with a stabilization appliance and the intra- articular injection of 2 ml of liquid phase concentrated growth factor with a stabilization appliance as a prolotherapy for temporomandibular joint anterior disc displacement without reduction.


Clinical Trial Description

Twenty four patients with anterior disc displacement without reduction will be selected from those attending the Prosthodontic Department, Faculty of Dentistry, Alexandria University and diagnosed clinically and by magnetic resonance imaging. Patients will be randomly assigned into 2 study groups each comprising 12 patients. Group I will receive an intra-articular injection of hypertonic dextrose in conjugation with a maxillary CAD/CAM full-arch hard clear acrylic stabilization appliance while group II will receive an intra-articular injection of LPCGF in conjugation with a maxillary CAD/CAM full-arch hard clear acrylic stabilization appliance. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04557878
Study type Interventional
Source University of Alexandria
Contact
Status Completed
Phase Phase 2
Start date October 6, 2020
Completion date June 1, 2021

See also
  Status Clinical Trial Phase
Recruiting NCT05006963 - Tele-Rehabilitation in Patients With Temporomandibular Dysfunction N/A
Completed NCT04102306 - Assessing Motor Imagery Ability of Tongue and Mouth in Subjects With and With no Temporomandibular Disorders
Not yet recruiting NCT05297604 - Non-Invasive Intravascular Laser Irradiation Of Blood In The Treatment Of Children With Temporomandibular Disorders Phase 2
Recruiting NCT03849534 - Treatment of Temporomandibular Disorders in Children and Adolsecents N/A
Recruiting NCT06035341 - The Association Between Temporomandibular Disorders and Sacroiliac Joint Dysfunction N/A
Not yet recruiting NCT05021874 - The Effect of Different Physiotherapeutic Stimuli on Stomatognathic System Structures. N/A
Recruiting NCT05232604 - How is Aerobic Exercise Compared to Localized Pain Relief Exercises in Patients With Jaw Pain and Neck Pain? N/A
Completed NCT03726060 - Effectiveness of Physical Teraphy in the Treatment of Myogenic Temporomandibular Disorders N/A
Not yet recruiting NCT06123351 - Forward Head Posture Correction Impact on Temporomandibular Dysfunction N/A
Completed NCT03619889 - The Effectiveness of a Physiotherapy Technique in Patients With Chronic Myofascial Temporomandibular Disorder N/A
Completed NCT01000389 - A Clinical Trial of the Optimal Treatment Period and Long-term Efficacy of Functional Electrical Stimulation (FES) on Sleep Bruxism N/A
Completed NCT00743223 - The Frequency Forward Head Posture in Subjects With Temporomandibular Disorder N/A
Completed NCT03300297 - Cervical Spine Thrust Joint Manipulation for Temporomandibular Disorder N/A
Completed NCT06065826 - Forward Head Posture and Myogenic TMD Association in Smartphone Overuse
Completed NCT04087005 - Efficacy and Safety of JHG002 for Chronic Temporomandibular Joint Dysfunction: A Multicenter Randomized Controlled Trial N/A
Recruiting NCT03696706 - Photobiomodulation With Red and Infrared LED Device for Temporomandibular Dysfunction Phase 2
Completed NCT04041271 - Jaw Kinematics and Muscle Activation in Patients With Non-specific Chronic Neck Pain
Recruiting NCT03096301 - Photobiomodulation in Temporomandibular Disorder N/A
Not yet recruiting NCT06052722 - The Relationship of Premenstrual Syndrome and Primary Dysmenorrhea With Severity of Temporomandibular Disorders N/A
Recruiting NCT05305833 - Stem Cells and Stromal Vascular Fraction for Temporomandibular Joint Disease Phase 1/Phase 2