TBI (Traumatic Brain Injury) Clinical Trial
Official title:
Classifying Neuro-imaging Measures Predicting Rehabilitation Outcome Following Pediatric Closed Head Injuries.
This project will combine the data collected from structural and functional MRI scans and neuropsychology performance post-TBI in children. Patients will be followed for a year, in order to examine the brain and cognitive recovery post head injury.
Traumatic brain injury in childhood has an cumulative effect that leads to impairments in cognitive functions such as deficits in memory, executive functions and attention. The cognitive impairment is the main cause of disabilities in the injured population, and has a different effect depending on the type and severity of the injury. Imaging after brain trauma serves as a useful diagnostic tool in identifying the head trauma's results. Therefore, in recent years, using imaging methods, studies have tried to find measures which will be able to predict the functional outcome after brain injury in children, and assist in developing a personalized rehabilitation program. The combination of advanced imaging techniques with neuropsychological assessment within the early stage of the injury and during a year of followup, will allow us to establish the relationship between those measures and the functional recovery result of the children. This multi-analysis will enable us to have a deeper understanding of the neuroplasticity process and the functional recovery after brain injury in the developing young brain. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04526639 -
VR Cognitive Rehabiliation for Pediatric TBI
|
N/A | |
Recruiting |
NCT05943756 -
Evaluation of Well-being Interventions in Adults With TBI
|
N/A | |
Completed |
NCT01339702 -
The EPIC Project: Impact of Implementing the EMS Traumatic Brain Injury Treatment Guidelines
|
||
Completed |
NCT00760734 -
Hyperbaric Oxygen Therapy (HBOT) in Chronic Traumatic Brain Injury (TBI)/Post Concussion Syndrome (PCS) and TBI/Post-Traumatic Stress Disorder (PTSD)
|
Phase 1 | |
Not yet recruiting |
NCT06024122 -
Brain Development in Young Children Following Mild Traumatic Brain Injury - Pilot Study
|
||
Completed |
NCT03896789 -
Pediatric Guideline Adherence and Outcomes- Argentina
|
N/A | |
Completed |
NCT03225768 -
Guided Training for People With Cognitive Impairment
|
N/A | |
Completed |
NCT04590911 -
Effectiveness of Multimodal Cognitive Rehabilitation for Traumatic Brain Injury Sustained During Older Adulthood
|
N/A | |
Recruiting |
NCT04121780 -
Growth Hormone Replacement Therapy for Retried Professional Football Players
|
Phase 2 | |
Completed |
NCT04776304 -
Art Therapy qEEG Study for Service Members With a Traumatic Brain Injury and Posttraumatic Stress Symptoms
|
N/A | |
Completed |
NCT00409058 -
Teen Online Problem Solving (TOPS) - An Online Intervention Following TBI
|
N/A | |
Completed |
NCT00205491 -
Pharmacological Intervention in Depression After Traumatic Brain Injury
|
Phase 4 | |
Completed |
NCT03490110 -
Brain Markers of Improvements in Cognitive Functioning
|
N/A | |
Active, not recruiting |
NCT02525432 -
Autologous Stem Cell Study for Adult TBI (Phase 2b)
|
Phase 2 | |
Completed |
NCT02858544 -
Concussion in Motor Vehicle Accidents: The Concussion Identification Index
|
N/A | |
Completed |
NCT01728831 -
Study of Cerebral Tissue Oxygenation During Transfusion in Traumatic Brain Injury
|
N/A | |
Recruiting |
NCT06005194 -
InMotion - Telehealth Delivered Exercise Promotion to Treat Major Depression After TBI
|
N/A | |
Not yet recruiting |
NCT05340803 -
Sedation of Ventilated Traumatic Brain Injury Patients With Midazolam Alone Versus Combination With Dexmedetomidine or Magnesium Sulfate; Monitored by Ultrasonograghic Optic Nerve Sheath Diameter
|
Phase 3 | |
Recruiting |
NCT06195345 -
Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1)
|
||
Recruiting |
NCT04279431 -
Follow-up of mTBI Patients Discharged From the ED Using Standard Clinical Triage Including BrainScope One
|