Clinical Trials Logo

Clinical Trial Summary

- Assess gustatory thresholds among a sample of depressed Egyptian adults (age from 20 to 50 years old) under anti-depressants therapy ( for at least 3 months) using filter paper disc(FPD) method through a scoring system. - Determine the taste intensity at supra-threshold among these patients using a psychophysical method through a scoring system. - Identify possible modulators for developing gustatory dysfunction among these patients using a questionnaire ( appendix) with a binary measuring unit (yes/no).


Clinical Trial Description

PECO - P Population: depressed Egyptian adults under anti-depressants therapy - E1 Exposure 1: commonly prescribed tricyclic antidepressants (Imipramine, Amitriptyline, Clomipramine HCL) - E2 Exposure 2: commonly prescribed Selective Serotonin Re-uptake inhibitors antidepressants ( Fluoxetine, Fluvoxamine, Sertraline, Citalopram, Paroxetine) - C control (non exposure) : non-pharmacological treatment ( psychotherapy) - O Outcome: Primary 1ry : Assess gustatory thresholds among a sample of depressed Egyptian adults (age from 20 to 50 years old) under anti-depressants therapy ( for at least 3 months) using filter paper disc(FPD) method through a scoring system. Secondary 2ry: - Determine the taste intensity at supra-threshold among these patients using a psychophysical method through a scoring system. - Identify gustatory dysfunction modulators among these patients using a questionnaire ( appendix) with a binary measuring unit (yes/no). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03599011
Study type Observational
Source Cairo University
Contact
Status Completed
Phase
Start date February 22, 2020
Completion date October 7, 2020

See also
  Status Clinical Trial Phase
Completed NCT04532632 - Taste and Smell Impairment in Critically Ill COVID-19 Patients
Completed NCT04145453 - Vegetables Intake and Polymorphism TAS2R38 Gene by Healthy Adults N/A
Recruiting NCT02931812 - Feeding Behavior and Taste Sensitivity Before and After Liver or Renal Transplantation
Not yet recruiting NCT04661800 - Study of Olfactory Disorders in Patients With Cardiac Amyloidosis N/A
Completed NCT04302792 - New Food Solutions for Cancer Patients N/A
Withdrawn NCT05760079 - Lactoferrin for COVID-19-Induced Taste or Smell Abnormality N/A
Completed NCT03196440 - Sensitivity of Basic Taste in Elderly
Completed NCT04235153 - CAncer, NUtrition and Taste - Validation of the CANUT-QVA Questionnaire on Eating Habits in Cancer Patients
Recruiting NCT02304913 - Hypoglossal Acupuncture for Dysgeusia in Patients Undergoing Chemotherapy N/A
Recruiting NCT04881513 - The Change of the Structure and Function of Taste Buds After the Otosclerosis Surgery N/A
Completed NCT04543175 - Taste Disorders and Their Relation to BMI, FFQ, and EORTC QLQ-BR23 in Breast Cancer Patients During Chemotherapy.
Completed NCT04923321 - Taste Supra-thresholds Among a Sample of Depressed Egyptian Adult Under Anti-depressants Therapy
Completed NCT04923425 - Gustatory Modulators Among a Sample of Depressed Egyptian Adults Under Anti-depressants Therapy
Completed NCT03498950 - Changes in Sense of Taste of Patients Submitted to Hematopoietic Stem Cell Transplantation N/A
Withdrawn NCT03043144 - Taste And Smell TEsting in End Stage Renal Disease N/A
Not yet recruiting NCT05104424 - The Study of Quadruple Therapy Intranasal Insulin, Zinc, Gabapentin, Ice Cube Stimulation for Post COVID-19 Smell and Taste Dysfunctions Phase 1
Completed NCT01540045 - Effect of Chemotherapy With Paclitaxel/Cisplatin on Development Dysgeusia in Non Small Cell Lung Cancer
Completed NCT05227157 - GOUTMETALSAIN: Comparison of the Perception of Metallic Taste According to Lingual Locations in Healthy Volunteers
Completed NCT00316563 - Orexigenic Therapy With Delta-9-tetrahydrocannabinol in Advanced Cancer Patients With Chemosensory Abnormalities - a Pilot Study Phase 2