Clinical Trials Logo

Clinical Trial Summary

It is commonly believed that a link exists between BMI and taste perception. One group of researchers observed that women who are obese experience reduced taste sensitivity when compared to normal-weight controls. Others have compared taste sensitivity between lean and obese subjects and found no significant differences. The inconsistencies in these studies demonstrate how much variation in taste sensitivity is possible when different factors are applied in research. Throughout several studies, one element remains constant - bariatric surgery causes appetite aversions. These changes in appetite and food preference likely have a large influence on the overall magnitude of post-surgical weight loss. Although many studies have investigated the changes in taste preference after bariatric surgery, few, if any, have focused on changes in sweet taste perception.


Clinical Trial Description

The overall goal of the present project is to determine how future bariatric surgery will affect the taste for sweet liquids. Taste perception will be assessed before surgery (pre-operative, pre-op) and after bariatric surgery, at approximately 1 month. Taste studies will be conducted with solutions prepared freshly before each test using sucrose dissolved in distilled water. Six concentrations of sucrose (table sugar) will be tasted in random order, with the most concentrated solution being roughly the sweetness of soda. The subject is blinded to the concentrations. It is hypothesized that there will be no significant difference in taste perception when pre-op and post-op values are compared. However, the investigators hypothesize that taste preference will identify solutions with lower concentrations post-op. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03548038
Study type Observational
Source University of Missouri-Columbia
Contact
Status Completed
Phase
Start date May 24, 2018
Completion date May 4, 2020

See also
  Status Clinical Trial Phase
Completed NCT04248374 - Fatty Acid Taste Rating With or Without Sour Taste Adaptation N/A
Completed NCT05518825 - Assessment of ONS-flavour Preference in Cancer Patients With and Without Taste Alterations N/A
Not yet recruiting NCT04606524 - Relationship Between MUC1 Expression and Gustatory Function in Postmenopausal Females
Completed NCT04263415 - The Effects of Semaglutide on Taste, Tongue Tissue Transcriptome, Gastric Emptying and Central Neural Response in Women With PCOS and Obesity Phase 4
Completed NCT05819073 - Astringency and Oral Health N/A
Completed NCT04107688 - Taste Perception, Salivary Proteins & the Oral Microbiome N/A
Completed NCT03501238 - Interaction of Salivary Proteins and Polyphenols N/A
Withdrawn NCT02617576 - Flavoring Oral Contrast for MR Enterography N/A
Completed NCT03824925 - Efficacy of Zinc on Concurrent Chemo-radiotherapy Induced Taste Alterations Phase 3
Completed NCT06089993 - Impact of Acute Resistance Exercise on Taste Perception and Appetite Response to Plant Protein in Resistance Trained Adults N/A
Recruiting NCT06287294 - An Investigation Into Taste Problems Associated With Xerostomia in Patients With Advanced Cancer
Completed NCT04629560 - Miracle Fruit Powder for the Treatment of Taste Alterations Secondary to Chemotherapy Early Phase 1
Not yet recruiting NCT04038281 - Genetics of Bitter and Fat Taste
Recruiting NCT06384365 - Interaction of Inflammation, Taste Perception and Preferences as a Function of Physical Activity and Body Composition