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Clinical Trial Summary

This is a double-blinded, two-arm, phase II study to assess efficacy, safety and tolerability of DFV890 in participants with symptomatic knee osteoarthritis. The study includes a screening period, a treatment period and a follow-up period. At most, the study duration is 21 weeks.


Clinical Trial Description

The purpose of the Phase 2a proof of concept study is to evaluate the safety and tolerability of DFV890 in participants with symptomatic knee OA, and to determine the efficacy of DFV890 in reducing knee pain as evidenced by change in KOOS (knee injury and osteoarthritis outcome score). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04886258
Study type Interventional
Source Novartis
Contact Novartis Pharmaceuticals
Phone 1-888-669-6682
Email novartis.email@novartis.com
Status Recruiting
Phase Phase 2
Start date September 20, 2021
Completion date April 7, 2025

See also
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Completed NCT01311206 - Low Intensity Resistance Training With Partial Blood Flow Restriction for Quadriceps Strengthening N/A