Suspected Arterial Hypertension Clinical Trial
Official title:
Central Blood Pressure Over 24 Hours (ABPM) and Left Ventricular Mas
Verified date | March 2015 |
Source | Klinikum Wels-Grieskirchen |
Contact | n/a |
Is FDA regulated | No |
Health authority | Austria: Federal Ministry for Health |
Study type | Observational |
The investigators aim to investigate whether central systolic blood pressure, as measured during regular 24 hour ambulatory blood pressure monitoring (ABPM), is a better predictor of left ventricular mass than peripheral systolic blood pressure during ABPM.
Status | Completed |
Enrollment | 350 |
Est. completion date | March 2015 |
Est. primary completion date | March 2015 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - 18 years of age, - no intake of antihypertensive medications - should have an indication for ABPM (suspected arterial hypertension) Exclusion Criteria: - no written informed consent - left ventricular hypertrophy due to other reasons than hypertension (hypertrophic cardiomyopathy, infiltrative cardiomyopathy, valvular heart disease, congenital heart disease) - inability to provide adequate echocardiographic readings - segmental contraction abnormalities of the left ventricle - contraindications for ABPM (lymphedema both arms) - other rhythm than stable sinus rhythm - unstable clinical condition, including recent severe infections |
Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Austria | Cardiology Department, University of Graz | Graz | |
Austria | Cardiology Department, Klinikum Wels-Grieskirchen | Wels | Upper Austria |
Germany | Cardiology Department, University of Lübeck | Lübeck | |
Greece | Sotiria Hospital 3rd Department of Internal Medicine | Athens | |
Italy | Department of Medical and Surgical Sciences, University of Brescia | Brescia | |
Italy | Clinica Medica, Hospitalo San Gerardo | Monza | |
Italy | Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia | Perugia | |
Spain | Hospital de Sagunto | Puerto de Sagunto | |
Switzerland | University of Basel | Basel | |
United Kingdom | Clinical pharmacology unit, University of Cambridge | Cambridge |
Lead Sponsor | Collaborator |
---|---|
Klinikum Wels-Grieskirchen | Austrian Society of Hypertension, European Regional Development Fund, I.E.M. (Stolberg, Germany) |
Austria, Germany, Greece, Italy, Spain, Switzerland, United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Left ventricular mass (m-mode echocardiography) | measured within 4 weeks from ABPM | No | |
Secondary | urine albumine / creatinine ratio | measured within 2 weeks from ABPM but before antihypertensive treatment is started | No |