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Influence of Perioperative Fluid Balance on Serum Concentrations of Antibiotics and Surgical Site Infections

Surgical Wound Infection Clinical Trial

Official title:
Influence of Perioperative Fluid Balance on Serum Concentrations of Antibiotics and Surgical Site Infections

Clinical Trial Summary

This study evaluates antibiotic serum concentrations in correlation with perioperative fluid balance. Patients will be recruited in rectum and esophageal surgery (representative for low blood loss and restrictive fluid management) and in liver surgery (representative for high blood loss and liberal fluid management). The hypothesis is that high blood loss and liberal fluid management dilute antibiotic serum concentrations thereby potentially increasing surgical site infections.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03408457
Study type Observational
Source Johannes Gutenberg University Mainz
Contact
Status Completed
Phase
Start date March 14, 2018
Completion date May 14, 2019
View Details
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