Surgical Wound Infection Clinical Trial
Official title:
Preoperative Oral Antibiotics and Surgical Site Infections in Colon Surgery Without Mechanical Bowel Preparation. A Prospective, Multicentre, Single Blinded, Randomized Trial (ORALEV Study)
Routine antibiotics for the intravenous and oral prophylaxis of colorectal surgery will be
used.
Experimental group: Patients undergoing elective colorectal surgery that involves, colonic
resection.
The antibiotic prophylaxis in this group will be composed of:
An oral antibiotic pattern of ciprofloxacin (750mg / 12h, 2 doses) and metronidazole (250mg /
8h, 3 doses) the day before surgery.
+
Control group: Patients undergoing elective colorectal surgery that involves, colonic
resection.
The antibiotic prophylaxis in this group will be composed of:
An intravenous antibiotic pattern of cefuroxime 1g and metronidazole 1,5gr during anesthetic
induction.
In both groups a second intravenous dose of cefuroxime (750mg) will be administered if the
intraoperative time elongates more than three hours or there is an intraoperative bleeding
over 1000cc.
There won´t be a placebo treatment. Subject compliance will be evaluated according to the
usual practice in surgical care field
n/a
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