Clinical Trial Details
— Status: Completed
Administrative data
| NCT number |
NCT05210920 |
| Other study ID # |
21-0027 |
| Secondary ID |
|
| Status |
Completed |
| Phase |
N/A
|
| First received |
|
| Last updated |
|
| Start date |
May 28, 2021 |
| Est. completion date |
May 31, 2023 |
Study information
| Verified date |
August 2023 |
| Source |
University of North Carolina, Chapel Hill |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Interventional
|
Clinical Trial Summary
Purpose: The purpose of this study is to evaluate if type of nail polish (gel polish or
regular polish) has an effect on the number of bacterial colonies on finger nails after
surgical scrubbing.
Participants: The potential participants are healthcare providers with patient interaction.
Exclusion criteria include evidence of active dermatitis or other skin abnormalities, or
allergy to chlorhexidine.
Intervention: Participants will have gel nail polish applied to one finger of their dominant
hand, and regular polish applied to another finger of their dominant hand. Bacterial swabs
will be collected from these two fingers, as well as the from the adjacent finger with no
nail polish. Specimen collection will occur both before and after scrubbing with surgical
soap. Bacterial counts will be compared between the three groups to determine the association
between the presence of nail polish and nail polish type on bacterial counts after surgical
scrubbing. Specimen collection will not take place during scrubbing for actual patient care.
Description:
Potential participants will be identified by word of mouth, flyers and institutional
networking. Once a participant agrees to enroll, they will have each type of nail polish
placed on a single finger on their dominant hand (gel on one finger and regular polish on
another). A third finger will be left bare to serve as a control. On day 1-3 after nail
polish application, the participant will have cotton swab samples taken from underneath their
nail and over their nail bed, on each of the two polished nails, as well as the adjacent bare
nail. These bacterial samples will be collected both before and after scrubbing (utilizing a
nail pick, scrub brush, and chlorhexidine). This process will be repeat on day 5-7 after nail
polish application. These samples will then be assessed for bacterial colonies in the
Microbiology laboratory. Participant variables will be recorded in RedCap (scrubbing
frequency, % of chipping in nails (in quartiles: 0, < 25%, < 50%, <75%, >75%, Gender, Age,
Level of training, Specialty, Type of polish, Dominant hand, Duration since application of
polish, Nail length in mm, Race, BMI, Type of bacteria isolated from samples).
Summary of Study Visits:
Day 0 Participants will have polish applied on two fingers on their dominant hand, one with
gel polish and one with regular polish.
Day 1-3 The participants will return for their first swabs. Bacterial swabs will be obtained
from the nail bed and under the fingernail of 3 fingers: the regular polish nail, the gel
polish nail and a bare nail adjacent to the two polished nails, before and after a standard
5-minute scrub with chlorhexidine.
Day 5-7 The participants will return for the same procedure described above. The nail polish
can be removed after this intervention. No further follow-up or involvement for participants
