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Clinical Trial Details — Status: Not yet recruiting

Administrative data

NCT number NCT03853096
Other study ID # H16-01432
Secondary ID
Status Not yet recruiting
Phase Early Phase 1
First received
Last updated
Start date April 1, 2019
Est. completion date April 1, 2020

Study information

Verified date February 2019
Source University of British Columbia
Contact William Regan
Phone 1-866-737-7460
Email bill.regan@ubc.ca
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The specific outcome is to determine whether the colony count of Propionibacterium acnes, one of the commonest causes of shoulder infection and not eradicated by conventional forms of surgical preparatory solutions and antibiotics, in a shoulder surgical wound will be altered by the use of subdermal cefazolin.


Description:

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Study Design


Intervention

Drug:
Cefazolin
Cefazolin 100mg/mL, 3mL in three locations will be administered around a surgical incision on the anterior shoulder in a standard deltopectoral approach interval. This will be a one time administration. Administration and route will be subcutaneous.

Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
University of British Columbia

References & Publications (10)

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Outcome

Type Measure Description Time frame Safety issue
Primary Change in P.acnes colony count Colony count before and 60 minutes after subcutaneous cefazolin administration Baseline tissue sampling prior to subcutaneous antibiotic administration, and tissue sampling 60 minutes after
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