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Decolonization to Reduce After-Surgery Events of Surgical Site Infection — DECREASE SSI  

Surgical Site Infection Clinical Trial

Official title:
Decolonization to Reduce After-Surgery Events of Surgical Site Infection

Clinical Trial Summary

The DECREASE SSI Trial (Decolonization to Reduce After-Surgery Events of Surgical Site Infection) is a two-arm multi-center individual placebo-controlled randomized (2,700 participants randomized 1:1) clinical trial to reduce post-discharge surgical site infection following open colon or small bowel surgery by comparing chlorhexidine bathing plus nasal mupirocin in the 30 days following discharge to soap without antiseptic properties (placebo) and placebo nasal ointment. This trial seeks to enhance the care of the 675,000 patients annually who undergo colon and small bowel surgery by finding simple and efficacious interventions to reduce SSI.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05586776
Study type Interventional
Source University of California, Irvine
Contact Susan Huang, MD, MPH
Phone (949) 824-5073
Email sshuang@hs.uci.edu
Status Recruiting
Phase Phase 4
Start date January 17, 2023
Completion date December 2028
View Details
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