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NCT05428579 Clinical Trial

Status of Surgical Resection and Histologic Subtype as Predictors of Local Recurrence in Retroperitoneal Liposarcoma

Surgical Procedure, Unspecified Clinical Trial

Official title:
Status of Surgical Resection and Histologic Subtype as Predictors of Local Recurrence in Retroperitoneal Liposarcoma - Case Series

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05428579
Other study ID # 29071984
Secondary ID
Status Completed
Phase
First received
Last updated
Start date October 1, 2017
Est. completion date November 1, 2018

Study information
Verified date June 2022
Source University of Sao Paulo General Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Soft tissue sarcomas are rare malignant tumors. Liposarcoma constitute the most frequent histological subtype of retroperitoneal sarcoma. The prognosis of soft tissue sarcomas depend on clinical and histologic characteristics. Objective: Evaluate variables that may be related to overall survival and local recurrence free survival in patients with retroperitoneal liposarcoma. Methods: retrospective analysis of medical records of 60 patients attended from 1997 to 2017, who underwent surgical resection of retroperitoneal liposarcoma.

Recruitment information / eligibility
Status Completed
Enrollment 60
Est. completion date November 1, 2018
Est. primary completion date October 1, 2018
Accepts healthy volunteers No
Gender All
Age group 17 Years to 76 Years
Eligibility Inclusion Criteria: - All patients who underwent surgical resection of retroperitoneal liposarcoma Exclusion Criteria: - Unresectable disease (upper mesenteric artery or vein involvement) or metastatic disease (sarcomatosis or distant disease)

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Retroperitoneal Liposarcoma resection
Retroperitoneal Liposarcoma resection

Locations
Country Name City State
Brazil Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo São Paulo

Sponsors (1)
Lead Sponsor Collaborator
University of Sao Paulo General Hospital

Country where clinical trial is conducted

Brazil, 

References & Publications (2)

Neuhaus SJ, Barry P, Clark MA, Hayes AJ, Fisher C, Thomas JM. Surgical management of primary and recurrent retroperitoneal liposarcoma. Br J Surg. 2005 Feb;92(2):246-52. — View Citation

Singer S, Antonescu CR, Riedel E, Brennan MF. Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma. Ann Surg. 2003 Sep;238(3):358-70; discussion 370-1. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary Overall survival rate 60 months
Primary Local recurrence-free survival rate 60 months
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