Perioperative Glucose and Insulin Changes in Major Urologic Surgeries — PEGLINS  

Surgery Clinical Trial

Official title: Perioperative Glucose and Insulin Changes in Major Urologic Surgeries

Status Completed

Clinical Trial Summary

Urological surgery patients will have their blood glucose measured before, during, and after surgery. Blood glucose will be measured using a continuous glucose monitor (CGM) device. We hypothesize the presence of a hyperglycemic state towards the end of surgery due to increased metabolic demand.

Clinical Trial Description

Surgical stress causes acute insulin resistance, increased circulating free-fatty acids, and reduced blood glucose uptake resulting in hyperglycemia. Intraoperative and postoperative glucose levels are typically only monitored in the diabetic or cardiac surgical patient. There is a lack of data on perioperative glucose levels in most prolonged surgeries and thus a barrier in determining the best glycemic management strategy to prevent or resolve acute insulin resistance and hyperglycemia. Obtaining blood glucose by CGM is less invasive and will avert disruption of current surgical pathways and standards of care while also producing reliable glucose measurements. ;

Related Conditions & MeSH terms

• Blood Glucose, High
• Surgery
• Urologic Diseases

• NCT number: NCT05222659
• Study type: Observational
• Source: University of Kansas Medical Center
• Status: Completed
• Start date: April 15, 2022
• Completion date: January 5, 2023