Surgery Clinical Trial
Official title:
Time Prediction for Complete Recovery From Neuromuscular Blockade After Visual Recovery With Double Burst Stimulation
The purpose is to calculate the time for an optimal recovery (T4/T1 > 0.9) from the moment when 2 responses to double burst stimulation are visually identical and this for 95% of patients.
Neuromuscular monitoring is a basic monitoring for all curarised patients. Acceleromiography
is used to supervise neuromuscular blockade and allow measuring in an objective and
quantitative manner the curarisation level during surgery and phase of recovery from
neuromuscular blockade. Various parameters are usually measured during surgery:
- T4/T1 ratio: ratio between the 4th and 1st response to "train of four" stimulation
(TOF, 4 stimulations of 0.2 ms in 2 s). Neuromuscular recovery is considered
appropriate if T4/T1 ratio is > 0.9
- Double burst stimulation (DBS): 2 short tetanic stimulations separated by an interval
of 750 ms.
It is known that when DBSs induce the same visual and/or tactile response, T4/T1 recovery
time is > 0.6. However, for an optimal recovery, T4/T1 ratio must be > 0.9.
This study will analyze the interval between the moment when DBSs are visually identical and
the T4/T1 ratio is > 0.9, from anesthesia sheet of patients undergone surgery with tracheal
intubation curarisation.
Results will define a minimum time to have an optimal recovery after having visually
identical DBS responses.
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Observational Model: Case-Only, Time Perspective: Prospective
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