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A Study of the Effect of Arterial Carbon Dioxide Tension on the Recovery of Spontaneous Respiration — RIP03  

Surgery Clinical Trial

Official title:
A Study of the Effect of Arterial Carbon Dioxide Tension on the Recovery of Spontaneous Respiration With Respiratory Inductance Plethysmography (RIP) During High Frequency Jet Ventilation (HFJV) Under General Anesthesia

Clinical Trial Summary

The investigators data reveal an important new observation regarding the recovery of breathing during emergence from general anesthesia: respiration resumes as a prolonged abdominal expiration event.

The present study aims to further clarify the physiology of recovery of breathing with the addition of a cutaneous monitor for arterial carbon dioxide measurement and a comparison of two different recovery paradigms.

Clinical Trial Description

The present study will use non-invasive respiratory inductance plethysmography(RIP) and transcutaneous carbon dioxide measurement to compare recovery of respiration under constant Transcutaneous carbon dioxide measurement( ptcCO2) with continuous high frequency jet ventilation HFJV (study method) with recovery of respiration during rising and apnea (current standard).

The investigators hypothesize that the prolonged abdominal expiration that we observed during recovery of breathing in prior studies will be unaffected by arterial carbon dioxide (CO2) levels. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01733446
Study type Interventional
Source University of Pennsylvania
Contact
Status Completed
Phase N/A
Start date September 2012
Completion date February 2018
View Details
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