Volume Deficit Prior to Surgery

Surgery Clinical Trial

Official title:

Estimation of Volume Deficit in Patients Prior to Surgery

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00380107
• Other study ID #: Opt. medium 1
• Status: Completed
• Phase: Phase 4
• First received: September 22, 2006
• Last updated: August 5, 2009
• Start date: October 2006
• Est. completion date: August 2007

Study information

• Verified date: August 2009
• Source: Rigshospitalet, Denmark
• Contact: n/a
• Is FDA regulated: No
• Health authority: Denmark: National Board of Health
• Study type: Observational

Clinical Trial Summary

It is the purpose of the researchers to identify the variation in intravascular deficits which can have relevance in high risk patients for minor and medium sized surgery.

The investigators will also estimate fluid deficit in healthy, non-fasting subjects for comparison.

Description:

Intravascular volume optimization has shown to improve outcome after surgery. In minor and medium surgery , however, the preoperative volume deficit has not been estimated with functional parameters. Patient scheduled for minor surgery are included. After the patient is anesthetized the intravascular volume is optimized by stroke volume maximization by colloid boluses. Stroke volume is obtained by esophageal Doppler technique which is a minimally invasive method.

The volume estimated for optimization is considered as the functional volume deficit.

In the healthy subjects the probe will be placed in the awake subject. A standardized meal and fluid intake secures that the subjects are in a non-fasting state.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 4
• Est. completion date: August 2007
• Est. primary completion date: August 2007
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• Planned minor or medium sized surgery

Exclusion Criteria:

• Oesophageal pathology

• Age >90 yr or < 18 yr

• Alcohol abuse,

• Insulin dependent DM

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

• Hypovolemia
• Surgery

Locations

Country	Name	City	State
Denmark	Rigshospitalet, ABD centret, anaesthesiological dept. 2041	Copenhagen

Sponsors (1)

Lead Sponsor	Collaborator
Rigshospitalet, Denmark

Country where clinical trial is conducted

Denmark,