Sunscreen: Persistence of Sun Protection Factor and the Influence on Vitamin D

Sunscreen Persistence Clinical Trial

— sunscreen  

Official title:

Sunscreen Removal by Clothing Meassured in Vivo. Sun Protection Factor Persistence During a Day Indoor Without Physical Activity. Does Sunscreen Reduce Vitamin D?

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT00711256
• Other study ID #: H-B-2007-120
• Status: Recruiting
• Phase: N/A
• First received: July 7, 2008
• Last updated: July 7, 2008
• Start date: July 2008
• Est. completion date: November 2008

Study information

• Verified date: April 2008
• Source: Bispebjerg Hospital
• Contact: Hans Christian Wulf, Dr.med
• Phone: +45 3135 3155
• Is FDA regulated: No
• Health authority: Denmark: Danish Dataprotection AgencyDenmark: Ethics Committee
• Study type: Interventional

Clinical Trial Summary

The investigators want to investigate whether sunscreen is removed by clothing and to what extend when the amount of sunscreen applied varies.Does clothing reduce the SPF when clothes are put on 20, 8, or 4 minutes after sunscreen application? The investigators also want to investigate the persistence of sunscreen during eight hours indoor. How much does the SPF reduces? Furthermore, we want to investigate whether sunscreen in the layers 2, 1, and 0.5 mg/cm2 reduce the vitamin D production in the skin.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 80
• Est. completion date: November 2008
• Est. primary completion date: August 2008
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Healthy participants.

• > 18 years.

• Skin type I, II, and III.

Exclusion Criteria:

• Pregnancy.

• Medicin use.

• Skin or other diseases.

• The participants must not have been in solarium or gotten sun on their trunks in the 3 months before the study start and during the study.

• Skin types IV and above.

Study Design

Allocation: Randomized, Intervention Model: Factorial Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

• Sunscreen Persistence
• Vitamin D Production in the Skin

Intervention

Other:
• sunscreen MATAS sunlotion SPF 8

Radiation:
• UVB light
duration 4 times 1 minute radiation on the trunk.

Locations

Country	Name	City	State
Denmark	Bispebjerg Hospital	Copenhagen	Kbh Nv

Sponsors (1)

Lead Sponsor	Collaborator
Bispebjerg Hospital

Country where clinical trial is conducted

Denmark, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	vitamin D (nmol) meassured in a blood sample.		5 days after sunscreen use and UV light exposure	No