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Circuit-Based Approach to Suicide: Biomarkers, Predictors, and Novel Therapeutics

Suicide Clinical Trial

Official title:
Circuit-Based Approach to Suicide: Biomarkers, Predictors, and Novel Therapeutics

Clinical Trial Summary

This neuroimaging study is a clinical trial investigating the effectiveness of intermittent theta-burst transcranial magnetic stimulation (iTBS-TMS) to the inferior parietal lobule (IPL) in reducing suicide risk in patients with major depressive episode (MDE) or borderline personality disorder (BPD).

Clinical Trial Description

This neuroimaging study aims to determine the effectiveness of iTBS-TMS to the IPL in reducing suicide risk in patients with MDE or BPD. This study also aims to identify the structural and functional circuit properties that characterized the suicidal brain and the signatures that explain the clinical severity of suicidal risk. Moreover, this study aims to determine biological and dimensional predictors of anti-suicidal response to iTBS-TMS and its mechanism of action. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04130958
Study type Interventional
Source Massachusetts General Hospital
Contact DNN Inbox
Phone 6177248780
Email mghdnn@mgh.harvard.edu
Status Recruiting
Phase N/A
Start date November 1, 2023
Completion date February 28, 2025
View Details
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