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Suicide clinical trials

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NCT ID: NCT03072875 Completed - Suicide Clinical Trials

CAMS-RAS: for Suicide Prevention

CAMS-RAS
Start date: December 18, 2015
Phase: N/A
Study type: Interventional

This Phase I feasibility study endeavors to create a prototype of a tool to determine its feasibility with suicidal patients in emergency departments (EDs). This is not a clinical trial. The overarching goal of this research is to create a tool that could reduce suicide rates, increase delivery of efficacious suicide interventions, and decrease overall costs associated with suicidal behaviors. SBIR Phase I project aims include: (1) creating an advisory board to guide the development of CAMS-RAS; (2) iteratively design and develop relational agent ("Dr. Dave") modeled after the gestures, expressions, and mannerisms of CAMS treatment developer, David Jobes, PhD; and (3) conduct feasibility tests to determine whether CAMS-RAS is acceptable, easy to use, and liked by target end-users: acutely suicidal patients admitted to hospital EDs, psychiatric inpatient units, and medical floors for treatment of injuries sustained during a suicide attempt; hospital medical personnel, administrators, and other stakeholders including peer advocates; and outpatient suicidal patients, clinicians and administrators.

NCT ID: NCT03069560 Completed - Clinical trials for Prevention of the Suicide

Short Message System (SMS) for Caregivers of Suicidal Patients to Prevent Recidivism of Suicide Attempts

C-SIAM
Start date: July 19, 2017
Phase: N/A
Study type: Interventional

Assessment of the feasibility of a monitoring device by SMS in which messages are sent by the caregiver after a suicidal act.

NCT ID: NCT03068598 Recruiting - Suicide, Attempted Clinical Trials

Suicide Sleep Monitoring (Ssleem)

SSLEEM
Start date: March 8, 2017
Phase: N/A
Study type: Interventional

Promising results have shown that interventions to reduce insomnia diminish suicidal ideation. A better understanding of the bidirectional mechanism between sleep disturbances and suicide behavior will allow the design of tailored interventions to prevent suicide attempts. Significance of the proposed study for the field The aim of the present is to assess the feasibility and the acceptability of sleep tracking monitoring in a sample of suicide attempters. The investigator hypothesize that sleep monitoring using a connected object is feasable and acceptable by patients.

NCT ID: NCT03043040 Completed - Suicide, Attempted Clinical Trials

Prevention of Suicidal Behaviour With Telemedicine Techniques

Start date: July 1, 2014
Phase: N/A
Study type: Interventional

This is a multicenter controlled intervention study that aims to assess the efficacy of a telephone follow-up program for the prevention of suicidal behavior in adults discharged from general hospitals after a suicide attempt. The hypothesis is that the implementation of this program is associated with reduced rates of suicide reattempts in these patients and also with delayed reattempts in them.

NCT ID: NCT03039192 Completed - Clinical trials for Depressive Disorder, Major

54135419SUI3001: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide

Aspire I
Start date: June 9, 2017
Phase: Phase 3
Study type: Interventional

The purpose of the study is to evaluate the efficacy of intranasal esketamine 84 milligram (mg) compared with intranasal placebo in addition to comprehensive standard of care in reducing the symptoms of Major Depressive Disorder (MDD), including suicidal ideation, in participants who are assessed to be at imminent risk for suicide, as measured by the change from baseline on the Montgomery-Asberg Depression Rating Scale (MADRS) total score at 24 hours post first dose.

NCT ID: NCT03034863 Completed - Suicide Clinical Trials

SAFER: A Brief Intervention Involving Family Members in Suicide Safety Planning

SAFER
Start date: July 3, 2017
Phase: N/A
Study type: Interventional

The management of suicide risk is a pressing national public health issue especially among Veterans, and there exist no guidelines of how best to involve family members in this effort. This proposal will integrate family and couples communication skills training with suicide safety planning. The goal is for the sharing of Veteran suicide safety plans with family members and the construction of a parallel family member safety plan, in efforts to mobilize and support family involvement.

NCT ID: NCT03030924 Recruiting - Suicide Clinical Trials

Wearable Suicidal Early Warning System for Adolescents

Start date: September 18, 2017
Phase:
Study type: Observational

This study is prospectively enrolling a cohort of adolescent patients who present to the Emergency Department and an inpatient psychiatric adolescent unit with acute suicidality.

NCT ID: NCT03027440 Active, not recruiting - Suicide Mortality Clinical Trials

The Developmental Origins of Suicide Mortality

Start date: January 10, 2017
Phase:
Study type: Observational

Background: Suicide rates are rising. In 2013, it was the third leading cause of death in children ages 10-14. It was the second leading cause of death for ages 15-24. Many risk factors for suicide have been found. But it is hard to predict. Evidence is growing that some factors that may make people vulnerable to suicide can be identified before birth or in early childhood. Researchers want to study vulnerability to suicide. They want to look at different kinds of development. These include prenatal, social, behavioral, cognitive, and neurologic. They will do this by linking data from the United States Collaborate Perinatal Project (CPP) to the National Death Index (NDI). The CPP data are from about 50,000 children born to mothers who enrolled in the 1960s. The CPP observed and examined about 60,000 pregnancies. Then it followed the babies from when they were born through age 7. The CPP collected data on things like family and medical history, economic status, and behavior. The NDI has data on the date and cause of death. Objective: To link data from the CPP to the NDI in order to study certain precursors to suicide. Eligibility: Offspring born to women who enrolled in the CPP in 1959-1966 and known to be alive at age 7 (Note: at the start of this study around in 2016, the youngest of those still alive would be 50 and the oldest would be 57 years old). Design: Data on children from the CPP will be submitted electronically to the NDI. It will be encrypted and data from the NDI will be deidentified to protect confidentiality. It will then be merged with existing CPP data. Researchers will analyze the data. ...

NCT ID: NCT03026387 Recruiting - Suicide Attempt Clinical Trials

Evaluation of the Risk Associated With Impulsivity and Other Neuropsychological Factors on Suicidal Relapse Within Hospital Emergencies

SUI-PREDICT
Start date: May 5, 2017
Phase: N/A
Study type: Interventional

Suicidal behavior (SB) is a major public health problem in France, with over 10,000 suicides (6th in the EU28) and 220,000 suicide attempts (SA) per year. These data seem underestimated by 20%. A large percentage of men (6%) and women (9%) in France made at least one lifetime SA. In addition, SBs are common among young people and are the second leading cause of death among 15-44 year-olds. The interaction of multiple factors in SB complicates the creation of predictive models. These are currently imprecise and prevent the development of consensual recommendations for the management of suicidal patients. Most suicide attempters are evaluated in the emergency room where it is imperative to identify people with a high risk of relapse. Risk assessment is generally based on the experience of the practitioner who uses psychometric scales as support for clinical decisions. This assessment could be improved and supplemented by other sources of information. Thus, we aim to develop a short and specific tool that combines: 1. Neurocognitive measures carried out using computer software on domains strongly associated with SB: impulsivity, affective dysregulation, alterations in decision-making (risky choices), selective attention and verbal fluency. 2. Clinical and psychological assessment including the most predictive items of future SA: life events (environment) and personality traits (vulnerability). Suicide attempters will be assessed for SB and suicidal ideation in the emergency department. These measures will be repeated during a 12-month follow-up. We will use the data obtained to provide a more accurate measure of risk.

NCT ID: NCT03026127 Recruiting - Suicide Prevention Clinical Trials

A Novel Cognitive Reappraisal Intervention for Suicide Prevention

CRISP
Start date: March 28, 2017
Phase: N/A
Study type: Interventional

The goal of this trial is to refine and test a novel emotion-regulation based psychosocial intervention designed to reduce suicide risk in middle-aged and older adults (50-90 years old) who have been discharged after a suicide-related hospitalization (i.e. for suicidal ideation or suicide attempt).