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Genetic Autopsy and Sudden Death — AGEMOS  

Sudden Death Clinical Trial

Official title:
Genetic Autopsy and Sudden Death of Young Subject

Clinical Trial Summary

The purpose of the study is to better identify hereditary cardiac causes of sudden unexpected death in young subjects through Next-Generation Sequencing of autopsy tissue

Clinical Trial Description

Monitoring :

For index cases group, all the data will be monitored. For the relatives group, only the informed consent will be monitored

Statistical analysis :

- Evaluate the additional elucidation rate of unexpected sudden death

- Evaluate causes obtained by Next Generation Sequencing (NGS) ( in comparison with conventional autopsy (macroscopic and / or microscopic)

- Descriptive study of the causes of sudden unexpected death, identified hereditary cardiac causes percentages compared via various diagnostic approaches

- Cost-effectiveness analysis

Data Management :

A database is created for the AGEMOS study with control of the discrepancies. All the index cases' data entered in the data base will be double checked ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02920203
Study type Observational
Source Assistance Publique - Hôpitaux de Paris
Contact Geoffroy Lorin de la Grandmaison, Pr
Phone +33(0)1 47 10 76 90
Email g.lorin@aphp.fr
Status Recruiting
Phase N/A
Start date October 11, 2017
Completion date December 2020
View Details
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