Predicting Dropout and Outcome From Neuropsychological Functions in SUD Patients

Substance Use Disorder (SUD) Clinical Trial

Official title: Predicting Early Treatment Termination (Dropout) and Post-treatment Clinical Outcome From Neuropsychological Functions in Abstinent Substance Use Dependent (SUD) Patients

Status Active, not recruiting

Clinical Trial Summary

The aim of this project is to gain a more specific understanding of how different cognitive profiles predict residential treatment drop-out, treatment retention and post-treatment outcome in a population with Substance Use Disorder.

Clinical Trial Description

This project collects the neuropsychological profile of residential SUD patients, in addition to treatment length, exit reason, hospital journal data and post-treatment clinical outcome data. The project aims to identify clinically relevant neurocognitive domains that predict treatment dropout and post-treatment clinical outcome. This will make it possible for future clinicians to focus their effort on neurocognitive functions most relevant for this particular patient group.

RESEARCH QUESTIONS:

1. What neurocognitive domain (and sub-domain) are the strongest predictor of treatment drop-out and retention?

2. What neurocognitive domain (and sub-domain) are the strongest predictor of post-treatment clinical outcome variables such as drug use, health and social integration.

3. Will data on treatment length, age, gender, substance abuse history or psychiatric co-morbidity predict outcome independently, or in interaction with, the neuropsychological profile?

This longitudinal prospective cohort study aims for a continuous collection of neuropsychological data baseline and post-treatment follow-up data until 2030. ;

Related Conditions & MeSH terms

• Substance Use Disorder (SUD)
• Substance-Related Disorders

• NCT number: NCT03220373
• Study type: Observational [Patient Registry]
• Source: Oslo University Hospital
• Status: Active, not recruiting
• Start date: March 7, 2017
• Completion date: December 31, 2029