Substance Abuse Clinical Trial
Official title:
Computer-based Brief Intervention for Perinatal Drug, Alcohol, and Tobacco Abuse
The purpose of the study is to see if a brief computer program can help new mothers cut down or quit tobacco, alcohol, or drug use.
The purpose of this Stage I/II intervention study (that is, Stage II for drug use and Stage
I for alcohol use and smoking) is to test the efficacy of a brief, computerized motivational
intervention for substance abuse among post-partum women. The study will randomly assign 350
post-partum women to either intervention or control conditions, with intervention itself
taking approximately 30 minutes in the period before the participant leaves the hospital.
Inclusion criteria will include post-partum status, age between 18 and 45, ability to
understand spoken English, and meeting criteria for one of the three substance use groups:
any illicit drug use in month prior to pregnancy, meeting T-ACE criteria for problem alcohol
use, or smoking in past month. Exclusion criteria will include receipt of narcotic pain
medication in the past 3 hours, no sleep since giving birth, and inability to provide
informed consent (e.g., due to psychosis or other clear cognitive impairment).
Lab-based follow-up will occur at 3- and 6-months postpartum. The primary outcomes will be
participant report of frequency of substance use and toxicological analyses of substance use
(urinalysis and expired breath CO at 3 and 6 month follow-up, hair analysis at 6-month
follow-up). Secondary outcome measures include HIV risk behaviors, receipt of treatment
services, motivation to change, self-efficacy, mental health functioning, violence exposure,
and consequences related to substance use.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT04070521 -
EEG Monitoring in the Emergency Department
|
||
| Completed |
NCT00729391 -
Women-Focused HIV Prevention in the Western Cape
|
Phase 2/Phase 3 | |
| Active, not recruiting |
NCT03129334 -
Preventing Prescription Drug Abuse in Middle School Students
|
N/A | |
| Completed |
NCT02733003 -
Implementation Research for Vulnerable Women in South Africa
|
N/A | |
| Completed |
NCT02573948 -
Feasibility of Interventions on People Who Inject Drugs in Vietnam
|
||
| Completed |
NCT02282306 -
Phone Interview to Prevent Recurring Opioid Overdoses
|
N/A | |
| Withdrawn |
NCT01847300 -
cSBI-M for Young Military Personnel
|
N/A | |
| Withdrawn |
NCT01523444 -
Advancing Adolescent Screening and Brief Intervention Protocols in Primary Care Settings
|
Phase 3 | |
| Completed |
NCT01481428 -
Reducing High Risk Behavior in Treatment Court
|
Phase 1 | |
| Completed |
NCT01591239 -
Home-Based Program to Help Parents of Drug Abusing Adolescents
|
N/A | |
| Completed |
NCT01601743 -
Exercise as a Behavioral Treatment for Cocaine Dependence
|
N/A | |
| Active, not recruiting |
NCT00847548 -
Treatment of Intimate Partner Violence and Substance Abuse in a Forensic Setting
|
N/A | |
| Completed |
NCT01614015 -
Building Outcomes With Observation-Based Supervision: An FFT Effectiveness Trial
|
Phase 2 | |
| Withdrawn |
NCT01228890 -
Primary Care Internet-Based Depression Prevention for Adolescents (CATCH-IT)
|
Phase 3 | |
| Completed |
NCT01621334 -
The Men's Domestic Abuse Check-Up Engages Adult Men Concerned About Their Abusive Behavior and Alcohol or Drug Use
|
Phase 1 | |
| Completed |
NCT00841711 -
Transitions: Linkages From Jail To Community
|
N/A | |
| Completed |
NCT00717444 -
Healthy Activities for Prize Incentives
|
N/A | |
| Completed |
NCT01188434 -
Integrating Interventions for Maternal Substance Abuse
|
Phase 1 | |
| Completed |
NCT01465490 -
Monitoring and Feedback in Substance Abuse Treatment
|
Phase 1/Phase 2 | |
| Completed |
NCT00318409 -
Acceptability of Pharmacologic Treatment for Methamphetamine Dependence Among MSM
|
Phase 2 |