The Genetic Basis for Vulnerability to Substance Abuse

Status Completed

Clinical Trial Summary

This investigation seeks to better define the genetic basis for vulnerability to substance abuse.

Clinical Trial Description

Dopamine (DA), a neurotransmitter helping to mediate reward and reinforcement, has been putatively linked to the development of substance abuse, alcohol abuse, and alcoholism. Identification of specific vulnerability-association alleles for receptors, other molecules within the reward mediating system, and other genes that may predispose individuals to the development of such disorders is the goal of the study.

This investigation will help elucidate the genetic underpinnings of substance abuse, potentially leading to the improved methods to diagnose those at risk and to help develop better therapeutic interventions. ;

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00247819
Study type	Observational
Source	National Institute on Drug Abuse (NIDA)
Contact
Status	Completed
Phase	N/A
Start date	August 1992
Completion date	February 2006

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