Preimplantation Genetic Testing for Aneuploidy of Polar Bodies

Status Recruiting

Clinical Trial Summary

This study intends to randomly group the patients with advanced maternal age and poor ovarian response, and the study group will undergo polar body biopsy, and the next-generation sequencing(NGS) technology will be used to evaluate the polar body euploidy and then predict the euploidy of the oocyte. Embryo transfer priority according to the NGS test results and morphological scores. In the control group undergo routine culture and the transfer priority is determined according to the morphological score only. The transfer of frozen embryos at the cleavage or blastocyst stage was permitted. Cumulative live birth rate, miscarriage rate and time required to obtain a live birth up to two ovulatory cycles in a year.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04538560
Study type	Interventional
Source	Reproductive & Genetic Hospital of CITIC-Xiangya
Contact
Status	Recruiting
Phase	N/A
Start date	October 20, 2020
Completion date	April 30, 2022

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