Motor Evoked Potential in the Affected Upper Limb Predicts the Potential of Motor Recovery in Subacute Stroke Patients

Stroke, Subacute Clinical Trial

Official title:

Motor Evoked Potential in the Affected Upper Limb Predicts the Potential of Motor Recovery in Subacute Stroke Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03243318
• Other study ID #: KHMEPsUL2017
• Status: Completed
• Start date: October 11, 2017
• Est. completion date: November 30, 2021

Study information

• Verified date: May 2022
• Source: Hospital Authority, Hong Kong
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Stroke is the third common cause of adult disability in dveloped countries. Early identification of the potential for motor recovery is important to avoid 'learned disuse' and to initiate appropriate therapy with achievable goals. The current cohort study focuses on those patients with SAFE <8 and using motor evoked potentials (MEPs) to improve on prognostication of upper limb motor recovery among subacute stroke patients in a local stroke population.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 32
• Est. completion date: November 30, 2021
• Est. primary completion date: October 31, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• First stroke with hemiparesis or hemiplegia with SAFE <8

Exclusion Criteria:

• contra-indication to TMS or MRI, history of seizure, pregnancy and mentally unfit to understand the consent

Related Conditions & MeSH terms

• Stroke
• Stroke, Subacute

Intervention

Diagnostic Test:
• MEPs induced by TMS
Using TMS induced MEPs over motor cortex of the affected side to predict motor recovery potentials

Locations

Country	Name	City	State
Hong Kong	Department of Rehabilitation, Kowloon Hospital	Hong Kong

Sponsors (1)

Lead Sponsor	Collaborator
Hospital Authority, Hong Kong

Country where clinical trial is conducted

Hong Kong, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Action Research Arm Test	Upper limb functional test	Change of Baseline Action Research Arm Test at 12 weeks post-stroke