Stress Clinical Trial - Effect of BrainPhyt, a Microalgae Based Ingredient

Status Completed

Clinical Trial Summary

In developed countries, the acceleration of the general population ageing has been widely described for decades, involving changes in public health policies. Among the health issues arising from this demographic change, the maintenance of cognitive function will be a major challenge in the next years, both in societal and economic terms. In this regard, some pharmacological and behavioural (e.g. physical activity, social involvement, intellectually demanding activities) preventive approaches have been evaluated to improve cognitive function with ageing. Among them, dietary interventions showed a potential interest to prevent cognitive decline during ageing. In this sense, there is a growing interest to find ecological solutions and to meet major societal challenge the use of microalgae as molecule of interest sources is a recent promising approach. Marine environments harbour a huge biological diversity of microalgae that represents a large source of almost untapped bioactive compounds. This biodiversity comprises 200,000 to 2 million species with about 35,000 which are described and 15,000 maintained in culture collections. Microalgae are able to produce bioactive molecules, such as pigments, fatty acids, peptides and sterols. Some of these compounds are unique and specifically found in the marine environment and they could be increasingly used as natural bioactive products for targeted applications. Fucoxanthin is one of the major carotenoid found in microalgae well known for its neuroprotective effect but to our knowledge no human studies were realized. Thus the objective is to evaluate, in healthy older adults, the effect of a 24-week period of daily supplementation of high and low BrainPhyt, doses on cognitive function parameters (Spatial Working Memory scores, Attention and vigilance, episodic memory, executive function), stress, mood, sleep quality and biomarkers.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04832412
Study type	Interventional
Source	Microphyt
Contact
Status	Completed
Phase	N/A
Start date	April 1, 2021
Completion date	May 20, 2023

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT05130944` - Feasibility of Community Psychosocial Intervention for Women	N/A
Recruiting	`NCT06079853` - Nurse Suicide: Physiologic Sleep Health Promotion Trial	N/A
Completed	`NCT05881681` - A Mindfulness Approach to UA for Afro-descendants	N/A
Recruiting	`NCT05449002` - Digital Single Session Intervention for Youth Mental Health	N/A
Recruiting	`NCT04038190` - A Behavioral Activation Intervention Administered in a College Freshman Orientation Course	Phase 2
Completed	`NCT03931772` - Online Automated Self-Hypnosis Program	N/A
Active, not recruiting	`NCT05998161` - Evaluating the Effectiveness of a Digital Therapeutic (Reviga) for People With Stress or Burnout	N/A
Completed	`NCT03728062` - Mindfulness Meditation Versus Physical Exercise: Comparing Effects on Stress and Immunocompetence	N/A
Terminated	`NCT04367636` - The Effects of Attention Training on Emotion Regulation and Stress Related Complaints During COVID-19	N/A
Completed	`NCT06405789` - The Effect of Yoga on Mindfulness and Perceived Stress	N/A
Recruiting	`NCT06002074` - SMART Program Impact on Quality of Life in Inflammatory Bowel Diseases	N/A
Recruiting	`NCT05273996` - Predictors of Cognitive Outcomes in Geriatric Depression	Phase 4
Completed	`NCT05245409` - Stress, EEG, ECG, and Chiropractic	N/A
Completed	`NCT04722367` - Being Present With Art: The Impact of Mindful Engagement With Art on Awareness and Connection	N/A
Recruiting	`NCT06273228` - Parenting Young Children in Pediatrics	N/A
Completed	`NCT06057883` - Effects Of A Probiotic Formulation On Stress and Skin Health in Younger Adult Females	Phase 2
Completed	`NCT05063305` - Probiotics, Immunity, Stress, and QofL	N/A
Completed	`NCT05312749` - The Effect of Web Based Progressive Muscle Relaxation Exercise on Clinical Stress and Anxiety of Nursing Students	N/A
Completed	`NCT05623826` - Feasibility and Efficacy of a Digital Training Intervention to Increase Reward Sensitivity- Imager	N/A
Completed	`NCT04013451` - The Kiss of Kindness Study II	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Effect of BrainPhyt, a Microalgae Based Ingredient on Cognitive Function in Healthy Older Subjects — PHAEOSOL-THREE

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms