Transmission of Mother-Infant Stress Communication

Stress Clinical Trial

— MIBLS  

Official title:

Transmission of Discrimination-Related Stress Reactivity and Reduction From Mother to Infant

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02013401
• Other study ID #: 2013173
• Status: Completed
• Start date: October 2013
• Est. completion date: July 14, 2016

Study information

• Verified date: October 2018
• Source: University of Massachusetts, Boston
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The central aim of this study is to assess mother-infant communication via behavioral, physiological, and affective indices under conditions where distal stressors may not be directly detectable by the infant.

Description:

This investigation examines a distal maternal stressor on the quality of interaction in mother-infant dyadic communication. Assessments include behavioral, physiological, and affective indices under conditions where distal stressors may not be directly detectable by the infant. The present research examines mother-infant interactions to test the hypothesis of whether maternal stress may be transduced to their infants via multiple pathways. The secondary aim is to explore effective emotion regulation strategies for the mother as potential buffers to stress and additionally reducing early life stress effects on the infant's regulatory development.

While the emotion regulation literature posits that reappraisal may be associated with decreased in physiological and psychological stress, this type of regulation strategy may be ineffective when interfacing with discrimination. The regulation strategy needs to be titrated to the stressor in order to be effective. These findings will have notable social, clinical, and psychological significance,

Recruitment information / eligibility

• Status: Completed
• Enrollment: 56
• Est. completion date: July 14, 2016
• Est. primary completion date: July 14, 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• Healthy volunteers

Exclusion Criteria:

• No presence of heart murmur or wear a pacemaker

• No medication for hypertensive or cardiovascular disease

• Not using beta blockers

Related Conditions & MeSH terms

• Stress

Locations

Country	Name	City	State
United States	University of Mass. Boston	Boston	Massachusetts
United States	University of Massachusetts, Boston, Child Development Unit	Boston	Massachusetts

Sponsors (1)

Lead Sponsor	Collaborator
University of Massachusetts, Boston

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Mother-infant observations	At four assessment occasions during the one time visit, the mother and infant are observed for a free 2-minute period. Observations include global affect, and (present or not) vocalizations, infant fussiness, and motor activity.	One lab appointment for approximately 80 minutes.
Primary	Salivary Cortisol	Salivary cortisol is a measure that indicates hypothalamus-pituitary-adrenal axis activity. The study obtains 4 assessments with 20 minutes between each assessment. Participants chew on a cotton role for 2-minutes which is placed in a cortisol salivette tube (Sarstedt)	One lab appointment for approximately 80 minutes.
Secondary	Salivary Amylase	Salivary amylase is an indicator of sympathetic nervous system activity. The same salivary salivette is used to later extract the amylase.	One lab appointment for approximately 80 minutes.