Evaluation of Plasma Catecholamine Concentration During Surgery

Stress Clinical Trial

Official title:

Evaluation of Stress Hormone Concentration During the Resection of Pheochromocytoma. Comparison of Surgeon - Anesthesiologist - Patient

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT00948181
• Other study ID #: 2009061
• Status: Active, not recruiting
• Phase: N/A
• First received: July 28, 2009
• Last updated: July 28, 2009
• Start date: June 2009
• Est. completion date: September 2010

Study information

• Verified date: July 2009
• Source: Kliniken Essen-Mitte
• Contact: n/a
• Is FDA regulated: No
• Health authority: Germany: Federal Institute for Drugs and Medical Devices
• Study type: Observational

Clinical Trial Summary

Stress during surgery leads to significant increase in plasma catecholamine concentrations in surgeons, anesthesiologists, and patients.

Description:

Hypothesis: Resection of pheochromocytomas can lead to more than normal stress in surgeons and because of abrupt hemodynamic changes in patients as well in anesthesiologists. Measurements of catecholamine concentrations at baseline, prior to surgery during and after surgery, are to be performed to test this hypothesis.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 8
• Est. completion date: September 2010
• Est. primary completion date: July 2010
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria: Patients with pheochromocytoma (Older than 18 years) -

Exclusion Criteria: Patients younger than 18 years. Conservative treatment.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Stress

Locations

Country	Name	City	State
Germany	Prof. Dr. Harald Groeben	Essen

Sponsors (2)

Lead Sponsor	Collaborator
Kliniken Essen-Mitte	Universität Duisburg-Essen

Country where clinical trial is conducted

Germany, 

References & Publications (2)

Schüttler J, Westhofen P, Kania U, Ihmsen H, Kammerecker S, Hirner A. [Quantitative assessment of catecholamine secretion as a rational principle of anesthesia management in pheochromocytoma surgery]. Anasthesiol Intensivmed Notfallmed Schmerzther. 1995 Oct;30(6):341-9. German. — View Citation

Unger N, Pitt C, Schmidt IL, Walz MK, Schmid KW, Philipp T, Mann K, Petersenn S. Diagnostic value of various biochemical parameters for the diagnosis of pheochromocytoma in patients with adrenal mass. Eur J Endocrinol. 2006 Mar;154(3):409-17. — View Citation