Stress Disorders, Post-Traumatic Clinical Trial
Official title:
The Efficacy of Stellate Ganglion Block as PTSD Therapy: A Pilot Study
RATIONALE: A stellate ganglion nerve block may help relieve symptoms of post-traumatic
stress disorder (PTSD).
PURPOSE: This pilot clinical trial is studying the efficacy of a stellate ganglion nerve
block in veterans to reduce the symptoms of PTSD in relatively long-standing (Vietnam era)
induced or relatively recently induced PTSD (from deployment in Afghanistan or Iraq as part
of Operations Enduring Freedom (OEF), Iraqi Freedom (OIF), and New Dawn (OND).
Objectives:
1. Stellate ganglion blocks will be performed in a small sample (n = 12) of the local
patient population that suffers from PTSD in order to replicate other preliminary
findings.
2. The parameters that lead to a successful treatment response will be evaluated by
comparing and contrasting the results obtained in younger (n=6) OEF/OIF generation
veterans versus older (n=6) Vietnam generation veterans.
3. The individual difference variables that might lead to successful treatment responses
will be studied by obtaining correlative measures of psychological and psychometric
data and responses to standardized tests.
Research Design:
This is an open label unblinded clinical pilot case series study to determine the efficacy
of stellate ganglion blockade for relief of PTSD symptoms in the Long Beach VA healthcare
population.
;
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Supportive Care
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