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NCT00174551 Clinical Trial

Feasibility Study: The Effect of Prazosin for Nighttime Symptoms of Civilian PTSD

Stress Disorders, Post-Traumatic Clinical Trial

Official title:
The Effect of Prazosin for Nighttime Symptoms of Civilian PTSD

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT00174551
Other study ID # 20031050
Secondary ID
Status Active, not recruiting
Phase N/A
First received September 9, 2005
Last updated September 7, 2006
Start date November 2003
Est. completion date November 2005

Study information
Verified date September 2005
Source Rainier Associates
Contact n/a
Is FDA regulated No
Health authority United States: Institutional Review Board
Study type Interventional

Clinical Trial Summary

Investigating the effect of prazosin for nighttime symptoms of civilian Posttraumatic Stress Disorder.

Description:

Each subject will receive prazosin and placebo trials, the order randomized. Day and nighttime symptoms will be monitored.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 20
Est. completion date November 2005
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group 18 Years to 80 Years
Eligibility Inclusion Criteria:

- must meet DSM-IV criterion for PTSD

Exclusion Criteria:

- Must not have untreated sleep apnea

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Drug:
• prazosin

Locations
Country Name City State
United States Fletcher B. Taylor Tacoma Washington

Sponsors (1)
Lead Sponsor Collaborator
Rainier Associates

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Sleep time
Primary REM sleep time
Primary Nightmare frequency
Primary CGI
Secondary Distressed Awakenings frequency
Secondary PCL-C
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