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Stomach Neoplasms clinical trials

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NCT ID: NCT03957486 Completed - Gastric Cancer Clinical Trials

Effect of Arterial Cannulation on the Continuous and Non-invasive Hemoglobin Monitoring

Start date: May 14, 2019
Phase: N/A
Study type: Interventional

The primary purpose of this study is to investigate the effect of arterial cannulation on the continuous and non-invasive hemoglobin monitoring during laparoscopic gastrectomy

NCT ID: NCT03957460 Completed - Gastric Cancer Clinical Trials

Accuracy of Continuous and Non-invasive Hemoglobin Monitoring

Start date: November 20, 2017
Phase:
Study type: Observational [Patient Registry]

The primary purpose of this observational study is to investigate the accuracy on the continuous and non-invasive hemoglobin monitoring during laparoscopic gastrectomy.

NCT ID: NCT03957096 Terminated - Colorectal Cancer Clinical Trials

A Safety Study of SGN-CD47M in Patients With Solid Tumors

Start date: July 17, 2019
Phase: Phase 1
Study type: Interventional

This trial will study SGN-CD47M to find out whether it is an effective treatment for different types of solid tumors and what side effects (unwanted effects) may occur. The study will have two parts. Part A of the study will find out how much SGN-CD47M should be given for treatment and how often. Part B of the study will use the dose found in Part A and look at how safe and effective the treatment is.

NCT ID: NCT03957031 Completed - Cancer, Gastric Clinical Trials

Gastric Cancer Risk Factors Associated With EU and CELAC Populations

LEGACY-1
Start date: May 31, 2019
Phase:
Study type: Observational

The study uses a case-control design that examines the differences in types of exposures between cases defined with a pathological confirmation of GC diagnosis, and controls, defined as patients to whom a gastroscopy was indicated and confirmed absent of GC i

NCT ID: NCT03954756 Not yet recruiting - Clinical trials for Advanced Gastric Cancer

Exploratory Clinical Study of Apatinib and PD-1 in Treating Advanced Gastric Cancer

Start date: June 1, 2019
Phase: Phase 2
Study type: Interventional

The Purpose of This Study is to Evaluate the Efficacy and Safety of Apafitini Combined With PD1 in Patients With Advanced Gastric Cancer After Second-line Treatment Failure, Thus Providing More Options for Patients With Advanced Gastric Cancer.

NCT ID: NCT03952442 Recruiting - Gastric Cancer Clinical Trials

Nutrition Education Program for Postoperative Patients With Gastric Cancer

Start date: February 21, 2019
Phase: N/A
Study type: Interventional

Using randomized control study, explore the effect of standardized nutrition education program on the nutrition status and life quality of patients with gastric cancer after surgery.

NCT ID: NCT03950908 Completed - Clinical trials for Hereditary Diffuse Gastric Cancer

Biopsy Technique for Endoscopic Surveillance of Hereditary Diffuse Gastric Cancer

Start date: October 12, 2017
Phase: N/A
Study type: Interventional

Germline mutation in e-cadherin gene (CDH1) is found in approximately 25% to 30% of individuals fulfilling the clinical criteria for hereditary diffuse gastric cancer (HDGC). Prophylactic gastrectomy is the mainstay of the management of cases with pathogenetic CDH1 mutation. However, some individuals refuse gastrectomy and prefer to delay it for medical or psychosocial reasons. For these patients as well as for those in which a pathogenetic mutation is not found, endoscopic surveillance is recommended. The suggested endoscopic protocol involves targeted as well as 30 random biopsies, which is tedious and time-consuming . In order to save time, two specimens can be taken during a single passage of the biopsy forceps ("double-bite" technique). The aim of this study was to determine the adequacy and utility of the "double-bite" technique in patients undergoing surveillance for HDGC as compared to the standard "single-bite technique".

NCT ID: NCT03950141 Recruiting - Clinical trials for HER-2 Negatived Gastric Cancer

Apatinib Combined With S-1 as Maintenance Therapy for HER-2 Negatived Gastric Cancer

Start date: July 1, 2017
Phase: Phase 2
Study type: Interventional

Apatinib is a novel drug which was produced by Jiangsu Hengrui Medicine Co.Ltd in China. It is approved in advanced gastric cancer(GC). The investigators just want to design such kind of trail to prove its effect when combined with S-1 as maintenance in advanced HER-2 negatived GC treated with 4 cycles chemotherapy and valued as SD. Investigators will evaluate progression free survival (PFS) and overall survival (OS).

NCT ID: NCT03949907 Recruiting - Clinical trials for GastroEsophageal Cancer

Early IntraVenous Administration of Nutritional Support

IVANS
Start date: April 14, 2020
Phase: N/A
Study type: Interventional

The present trial will be conducted to verify if early supplemental parenteral nutrition in combination with nutritional counseling improves survival and the feasibility of chemotherapy, in addition to nutritional status, body composition, functional status and quality of life in treatment-naïve patients with metastatic gastric cancer at nutritional risk undergoing first-line chemotherapy.

NCT ID: NCT03941561 Recruiting - Gastric Cancer Clinical Trials

S-1 for 9 Months Versus 1 Year for Stage II Gastric Cancer (SMAC)

Start date: January 1, 2019
Phase: Phase 3
Study type: Interventional

The study aims to compare the efficacy and safety of S-1 for 9 months versus S-1 for 1 year as adjuvant chemotherapy after D2 resection in patients with gastric cancer. Hypothesis: For gastric patients after D2 resection, S-1 for 9 months shows non-inferiority to S-1 for 1 year in disease-free survival(DFS), overall survival (OS) and safety.