Intensive Statin Treatment for STEMI Patients Undergoing Primary PCI

STEMI Clinical Trial

Official title: Effect of Intensive Statin Treatment on 90-day Prognosis of STEMI Patients Undergoing Emergency Primary PCI Compared With Usual Care

Status Not yet recruiting

Clinical Trial Summary

This is a retrospective, randomized, parallel, open-labeled, controlled study to find out whether STEMI patients undergoing emergency PCI can benefit from intensive atorvastatin treatment compared with routine treatment.

Clinical Trial Description

ARMYDA-ACS, ARMYDA-RECAPTURE and NAPLES II demonstrated that in patients with ASP and NSTE ACS undergoing early PCI, loading dose of atorvastatin before early PCI led to a reduction of prei-PCI MI, recurrent CV events and mortality. While, theses studies included patients with non-ST-segment elevation ACS, requiring PCI; these results cannot be extrapolated directly to patients with ST-segment elevation MI, and these trials included patients sent to an early and selective PCI, but not those undergoing emergency revascularization;

This study is designed to find out whether STEMI patients undergoing emergency PCI can benefit from intensive atorvastatin treatment compared with routine treatment. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• STEMI

• NCT number: NCT01033058
• Study type: Interventional
• Source: Beijing Chao Yang Hospital
• Contact: Xinchun Yang, Prof.
• Phone: +86 10 85231937
• Email: yangxc@medmail.com.cn
• Status: Not yet recruiting
• Phase: Phase 4
• Start date: December 2009
• Completion date: June 2011