Stargardt Disease Clinical Trial
Official title:
Natural History of Progression of Atrophy Secondary to Stargardt Disease: Retrospective, and Prospective Longitudinal Observational Study Incl. Ancillary SMART Study- Scotopic Microperimetric Assessment of Rod Function in Stargardt Disease
Stargardt disease is currently an incurable and untreatable macular dystrophy that causes
severe visual loss in children and young adults, thereby causing enormous morbidity with
economic, psychological, emotional, and social implications. There are no FDA approved
therapeutic treatments for this disease. Therefore, the objective of this study is to collect
natural history data from a large population of children and adults in order to evaluate
possible efficacy measures for planned clinical trials.
Participants will be recruited from each Investigator's own patient population as the study
requires the availability of both multiyear retrospective data, as well as ongoing
prospectively collected data. A concurrent ancillary study (SMART study) is also being
conducted with a subset of the prospective study patients during their regular ProgSTAR study
visits to expand the collection of retinal images to include microperimetry measurements
gathered under scotopic (low light) conditions.
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