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NCT04574752 Clinical Trial

MSSA and MRSA Screening in Patients Undergoing Elective TJA: the Benefits of Next-generation Sequencing

Staphylococcus Aureus Clinical Trial

Official title:
MSSA and MRSA Screening in Patients Undergoing Elective TJA: the Benefits of Next-generation Sequencing

Clinical Trial Details — Status: Enrolling by invitation

Administrative data
NCT number NCT04574752
Other study ID # JPARV20D.165
Secondary ID
Status Enrolling by invitation
Phase
First received
Last updated
Start date August 30, 2020
Est. completion date August 30, 2021

Study information
Verified date September 2020
Source Rothman Institute Orthopaedics
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The aims of this study were to evaluate the diagnostic performance of molecular and culture techniques in S. aureus screening using paired nasal and groin swabs, to determine, if any, discrepancy between the diagnostic techniques and to model the potential effect of different diagnostic techniques on S. aureus detection in orthopaedic patients

Recruitment information / eligibility
Status Enrolling by invitation
Enrollment 163
Est. completion date August 30, 2021
Est. primary completion date August 30, 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 80 Years
Eligibility Inclusion Criteria:

- All patients undergoing primary total knee or total hip arthroplasty at our institution will be eligible.

Exclusion Criteria:

- Patients included in other prospective studies

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• next generation sequencing
diagnostic performance of molecular and culture techniques in S. aureus screening using paired nasal and groin swabs, to determine, if any, discrepancy between the diagnostic techniques on S. aureus detection in orthopaedic patients

Locations
Country Name City State
United States Rothman Orthopaedic Institute Philadelphia Pennsylvania

Sponsors (1)
Lead Sponsor Collaborator
Rothman Institute Orthopaedics

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Diagnostic techniques to identify S. aureus in total joint replacement patients to model the potential effect of different diagnostic techniques on S. aureus detection in orthopaedic patients. 1 day
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