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Prospective Study of Staphylococcus Aureus Clinical Isolates Versus Colonization: RNAs as Potential Biomarkers for Bloodstream Infections — PROSAC  

Staphylococcus Aureus Clinical Trial

Official title:
Prospective Study of Staphylococcus Aureus Clinical Isolates Versus Colonization: RNAs as Potential Biomarkers for Bloodstream Infections

Clinical Trial Summary

The primary objective is to demonstrate that the risk of S. aureus bacteremia (SAB) is correlated to the RNA III and SprD RNAs expression

Clinical Trial Description

Staphylococcus aureus ranks among the top three organisms for community-acquired, healthcare-related and nosocomial infections in humans. It lives as a commensal organism but can also provoke very severe diseases. Identifying markers of the 'colonization/disease' transition is of paramount importance. We recently found that an association of two regulatory RNAs was associated with S. aureus infection rather than colonization and with the severity of infection. Those preliminary results have to be confirmed with a more important prospective cohort. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03833102
Study type Observational
Source Rennes University Hospital
Contact
Status Completed
Phase
Start date February 21, 2018
Completion date February 22, 2023
View Details
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